Rabbit production in Bulgaria

Dimitrova, I.; Dimitrov, T; Teneva, Atanaska; Tzvetkova, H.

doi:10.2298/bah0802149d

Cited by 4 publications

(2 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The next larger import of rabbits of the Californian breed took place in 2002, again from Italy (Marinov et al, 2009), the offspring of which are the experimental animals in this study. At present, a total of 842 Californian rabbits (705 does and 137 bucks in 10 herds) are under the selection control of the Executive Agency for Selection and Reproduction in Animal Breeding in Bulgaria and rabbit breeding activities are carried out by different breeding associations (Grigorov, 2005;Dimitrova et al, 2008;EASRAB, 2017).…”

Section: Introductionmentioning

confidence: 99%

Association analysis of nucleotide polymorphisms in growth hormone (GH) and its receptor (GHR) with body weight in Californian rabbits

2022

View full text Add to dashboard Cite

The objective of the present study was to evaluate the influence of the genotypes of two single nucleotide polymorphisms (SNPs) – c.78C>T located in the growth hormone gene (GH) and c.106C>G in the growth hormone receptor gene (GHR) on individual body weight (IBW) during the growing period at 35, 70 and 90 d of age on a total of 107 weaned Californian breed rabbits. The restriction fragments obtained revealed that 74.8% of the rabbits carrying c.78C>T SNP and 52.3% of the rabbits carrying c.106C>G SNP were heterozygous, which indicated a moderate level of genetic diversity in this Californian population. Association analysis based on a single-gene approach revealed that c.78C>T polymorphism in the GH gene had a significant effect (P<0.05) on the weight at 70 and 90 d of age. The highest IBW (2530.4±66.6 g) was observed in rabbits carrying the c.78C>T TT genotype, and detected individuals were significantly affected by the dominance effect. Significant differences were observed between individuals with homozygous c.106C>G CC genotype and those with heterozygous CG genotype. The highest IBW (2462.0±198.3 g) was observed in rabbits carrying the c.106C>G CC genotype and detected individuals were significantly affected by the additive effect. A total of nine combined genotypes of c.78C>T and c.106C>G SNPs was found in the study, of which only four major groups (CT/CC, CC/CG, CT/CG, and CT/GG) were concerned in the diplotype analysis. Significant differences were observed between individuals with CT/CC and CC/CG genotype combinations, and between those with the CC/CG and CT/GG diplotypes. However, the highest IBW at 90 d of age (2447.2±213.8 g) was observed in rabbits carrying the CT/CC genotype combinations. The highest coefficient of determination found for individual body weight at 90 d of age (R2=10.8%) indicated a high effect of genotype combinations. In conclusion, the results obtained suggested that c.78C>T of GH gene and c.106C>G of GHR gene could be useful candidate genes to improve growth performance in Californian rabbits with potential application in rabbit breeding programmes.

show abstract

Section: Introductionmentioning

confidence: 99%

Association analysis of nucleotide polymorphisms in growth hormone (GH) and its receptor (GHR) with body weight in Californian rabbits

2022

View full text Add to dashboard Cite

show abstract

“…Nowadays, 99.4% of the rabbit population is reared in private farms, while the rest are raised in governmental farms (primarily research institutes). New Zealand White and Californian breed represent the majority of the rabbit population in the country (Dimitrova et al, 2008). World Rabbit Sci.…”

Section: Introductionmentioning

confidence: 99%

Identification of nucleotide variation of growth hormone gene in rabbit populations reared in Bulgaria

Hristova

Koynarski

Dafova³

et al. 2021

World Rabbit Sci.

View full text Add to dashboard Cite

Five rabbit populations of New Zealand White (NZW), Californian (CAL), crossbred NZW×GW and two generations of the synthetic population – SPF1 and SPF2 reared in Bulgaria were included in the present study with the aim of detecting the genetic variability of the growth hormone encoding gene (GH) via polymerase chain reaction with the restriction fragment length polymorphism analysis and direct sequencing. The targeted region of the rabbit GH gene was amplified and a fragment of a total of 231 bp was obtained in all studied populations. Allele identification was determined after enzymatic digestion, where two fragments of 62 and 169 bp correspond to allele C and an undigested fragment of 231 bp corresponds to allele T. Two additional bands of 107 and 124 bp evidenced A/G genetic polymorphism in the rabbit GH gene. Thirtyeight percent of the studied rabbits were carriers of the double mutation (C/T+A/G) in the same locus as the studied GH gene. The sequence analysis revealed two nucleotide substitutions – g.111C>T and g.156A>G in the non-coding region between the regulatory TATA box and 5’ UTR region, and a novel g.255G>A genetic variant in intron 1 of GH gene. The A>G transition was most frequent (40.57%), compared to the other ones, G>A (28.57%) and C>T (10.80%), respectively. The most frequent genotype in the NZW population was homozygous TT (0.93), with a prevalence of the T allele (0.97) over allele C (0.03) for g.111C>T SNP site. The distribution of the allele and genotype frequencies at the sites g.156A>G and g.255G>A in this rabbit group was identical, with the highest value of 0.93 for alleles A and G, respectively. The rabbit populations CAL and NZW×GW showed equal frequencies of the prevalent T allele (0.83) and for homozygous TT genotype (0.67) according to g.111C>T SNP. The highest values were obtained for the allele А (0.83) and for homozygous AA genotype (0.67) at c.33A>G SNP in these rabbit groups. The highest values (0.67, 0.60 and 0.80) for the heterozygous genotypes at g.111C>T, g.156A>G and g.255G>A SNPs, respectively, were detected among the SPF2 rabbit population, compared to the both homozygous genotypes. The results obtained in the present research indicates a significant degree of genetic variability of the studied polymorphic GH locus in the SPF2 rabbit group.

show abstract

Farming of rabbit local breed as an alternative activity on small scale farms in Albania

Llambiri¹,

Papa

Kume³

2010

BIOTEC ANIM HUSB

View full text Add to dashboard Cite

Rabbit breeding on small scale family farms is carried on as an alternative production activity, in Albania. Extensive production system and breeding of local rabbit breed are most frequent. Albanian local rabbit can be classified in middle size breed group. It is a population with high morphological and biological variability, with variation in coat colour. Rabbit farming is a useful production activity on small scale family farms. Breeding 2-3 couples of reproducing rabbits could increase the gross annually income of family farm up to 22-28 percent.

show abstract

Rabbit production in Bulgaria

Cited by 4 publications

References 3 publications

Association analysis of nucleotide polymorphisms in growth hormone (GH) and its receptor (GHR) with body weight in Californian rabbits

Association analysis of nucleotide polymorphisms in growth hormone (GH) and its receptor (GHR) with body weight in Californian rabbits

Identification of nucleotide variation of growth hormone gene in rabbit populations reared in Bulgaria

Farming of rabbit local breed as an alternative activity on small scale farms in Albania

Contact Info

Product

Resources

About