Rabbit Colony Management and Related Health Concerns

Quinn, Robert H.

doi:10.1016/b978-0-12-380920-9.00009-2

Cited by 4 publications

(12 citation statements)

References 69 publications

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“…In all animals, in vivo imaging of anatomy and placental pyruvate metabolism was performed with hyperpolarized MRI, as pyruvate, lactate, alanine and bicarbonate are fundamental intermediates in the metabolism of glucose (figure 3a) [38]. MRI was performed with a 3T system (GE Healthcare, Waukesha, WI, USA) equipped with a 1 H 8-channel cardiac array coil for anatomical (T2-weighted) scans and a 13 C Helmholtz loop coil (ø = 20 cm) for metabolic maps of endogenous substrates using hyperpolarized MRI. Hyperpolarized MRI is a method for assessing metabolic processes in tissues in real time.…”

Section: Hyperpolarized Mrimentioning

confidence: 99%

“…Hyperpolarized MRI is a method for assessing metabolic processes in tissues in real time. In vivo imaging of the chinchilla placenta was performed with standard 1 H-MRI, allowing visualization of the fetus and placenta, and hyperpolarized 13 C-MRI for assessment of pyruvate metabolism (figure 3a) [39]. Two millilitres of 90 mM [1-13 C]-pyruvate were injected into the tail vein catheter over a period of 15 s. A slice-selective 13 TR/TE/ TE = 100 ms/0.9 ms/0.9 ms, FOV = 120 × 120 mm 2 , 5 × 5 mm 2 real resolution and an axial slice thickness of 20 mm covering the placenta and a part of the fetus.…”

Section: Hyperpolarized Mrimentioning

confidence: 99%

“…In vivo imaging of the chinchilla placenta was performed with standard 1 H-MRI, allowing visualization of the fetus and placenta, and hyperpolarized 13 C-MRI for assessment of pyruvate metabolism (figure 3a) [39]. Two millilitres of 90 mM [1-13 C]-pyruvate were injected into the tail vein catheter over a period of 15 s. A slice-selective 13 TR/TE/ TE = 100 ms/0.9 ms/0.9 ms, FOV = 120 × 120 mm 2 , 5 × 5 mm 2 real resolution and an axial slice thickness of 20 mm covering the placenta and a part of the fetus. The temperature, saturation and respiration were monitored during MRI, and the animal was heated with a temperature-controlled heater (SA Instruments, Stony Brook, NY, USA).…”

Section: Hyperpolarized Mrimentioning

confidence: 99%

“…After the last MRI scan, each chinchilla was euthanized using pentobarbituate, and it was secured that the fetus was dead. MRI analyses included regionsof-interests of placenta, fetus, maternal skeletal muscle tissue and noise that were manually drawn on the 1 H anatomic images in OsiriX (The Osirix Foundation, Geneva, Switzerland, http://www.osirixviewer.com) [40] and transferred to the 13 C images (figure 3b,c). The ROI signal intensities were analysed according to signal-to-noise ratio, by dividing the sum of the pyruvate signals with the mean of the noise signal for each metabolite.…”

Section: Hyperpolarized Mrimentioning

confidence: 99%

“…The litter size of 1–6 cubs is small for a rodent [ 8 ] ( figure 1 a , b , d ) and very often chinchillas will carry only one offspring. Furthermore, the gestation period of 105–115 days [ 8 ] is long compared with other established rodent models, such as the guinea pig (59–72 days [ 9 ]), rat (21–23 days [ 10 ]), mouse (19–20 days [ 11 ]), hamster (15.5 days [ 12 ]) and even the approximately threefold larger lagomorph rabbit (29–35 days [ 13 ]; figure 1 a , c , d ). The relatively long gestation period allows higher temporal investigations of the placenta and the fetus, and the small litter size circumvents the challenge of pairing individual measurements on the placenta and fetus over time in longitudinal experiments.…”

Section: Introductionmentioning

confidence: 99%

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The chinchilla as a novel animal model of pregnancy

et al. 2017

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Several parameters are important when choosing the most appropriate animal to model human obstetrics, including gestation period, number of fetuses per gestation and placental structure. The domesticated long-tailed chinchilla (Chinchilla lanigera) is a well-suited and appropriate animal model of pregnancy that often will carry only one offspring and has a long gestation period of 105–115 days. Furthermore, the chinchilla placenta is of the haemomonochorial labyrinthine type and is therefore comparable to the human villous haemomonochorial placenta. This proof-of-concept study demonstrated the feasibility in laboratory settings, and demonstrated the potential of the pregnant chinchilla as an animal model for obstetric research and its potential usefulness for non-invasive measurements in the placenta. We demonstrate measurements of the placental and fetal metabolism (demonstrated in vivo by hyperpolarized MRI and in vitro by qPCR analyses), placental vessels (demonstrated ex vivo by contrast-enhanced CT angiography) and overall anatomy (demonstrated in vivo by whole-body CT).

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Section: Hyperpolarized Mrimentioning

confidence: 99%

Section: Hyperpolarized Mrimentioning

confidence: 99%

Section: Hyperpolarized Mrimentioning

confidence: 99%

Section: Hyperpolarized Mrimentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The chinchilla as a novel animal model of pregnancy

et al. 2017

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Current perspectives in avian nutrition: domestic animal models and their role in conservation management

Jarman,

Shaw,

Grueber

2023

Ibis

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As biodiversity declines, wildlife conservation focuses on in situ and ex situ management strategies. Zoo‐based breeding programmes are often designed to contribute to the conservation of species that are threatened in the wild. Diet contributes to the reproductive success, disease status and longevity of all animals. It is near‐impossible to replicate a species' diet in captivity using only the species they consume in the wild, but the nutritional composition of a wild diet, if known, can be closely matched using commercially available foods for which the nutritional composition has been calculated. Ecological research has identified food items of importance in the diet of many species. However, the nutritional composition of these food items is rarely evaluated, even though the composition of wild food items is important in understanding the dietary adaptations and requirements of wildlife. In contrast, the nutritional requirements of domestic species are well researched and can be used to predict a range of plausible nutrient requirements of some wild species, especially those with similar life histories. Access to wild populations provides further opportunities for nutritional science to determine the requirements of individual species. Small‐scale dietary experimentation undertaken at conservation institutions may show positive effects on health and welfare but is rarely published in the scientific literature. This review describes current standards in nutritional management of birds and recommends pathways for filling knowledge gaps. Research on mammals has dominated the nutrition literature, so there is a relative lack of nutritional management information for birds. We combine concepts of domestic animal nutrition with recent findings on the nutritional requirements of birds to provide a foundation for further studies of avian nutrition. We call for the broader zoological community to share data and collaborate on nutritional research to support conservation institutions in nutritional management of wild birds.

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Arsénico, cadmio, mercurio y plomo en alimentos importados para mascotas en Costa Rica

Naranjo-Jiménez

WingChing-Jones

2022

Agron. Mesoam.

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Introducción. El consumo de metales pesados puede provocar problemas de salud en los animales. Objetivo. Determinar la concentración de cadmio, mercurio, plomo y arsénico en 34 alimentos balanceados importados y comercializados en Costa Rica para perros, gatos, conejos, hámsteres, tortugas y peces ornamentales. Materiales y métodos. Se cuantificó el contenido de arsénico (As), cadmio (Cd), mercurio (Hg) y plomo (Pb) en alimentos balanceados importados para seis animales de compañía, durante los meses de mayo a octubre del año 2018. De forma aleatoria, se visitaron expendios autorizados de alimentos balanceados y se compraron diez empaques de alimento para perros y gatos, cinco para peces ornamentales, cuatro para tortugas, tres para hámsteres y dos para conejos. Las muestras fueron analizadas en el Centro de Investigación en Nutrición Animal de la Universidad de Costa Rica mediante espectrofotometría de absorción atómica con atomizador de tubo de grafito (As, Cd, Pb) y de celda de cuarzo (Hg). Resultados. Las concentraciones obtenidas en alimentos para perros y gatos, adultos y cachorros, conejos, hámsteres, peces ornamentales y tortugas, fueron para As de 0,009, 0,013, 0,003, no detectable (ND), ND, 0,036 y 0,113 ppm, respectivamente; para Cd de ND, 0,021, 0,022, 0,031, 0,010, 0,037, 0,139 y 0,043 ppm, respectivamente; para Hg de 0,101, 0,078, 0,045, 0,040, 0,031, 0,045, 0,032 y 0,032 ppm, respectivamente, y para Pb de 0,381, 0,885, 0,573, 0,740, 0,446, 0,732, 0,763 y 0,841 ppm, respectivamente. Conclusión. Los contenidos de metales pesados determinados en alimentos para mascotas, no superaron los valores máximos permitidos para su comercialización. Este trabajo incrementa la información disponible en temas de inocuidad de alimentos balanceados en peces ornamentales, hámsteres, tortugas y conejos; promueve estrategias de monitoreo continuo de estos y la comprensión del potencial real de acumulación en los animales y sus efectos en el bienestar de los mismos.

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Rabbit Colony Management and Related Health Concerns

Cited by 4 publications

References 69 publications

The chinchilla as a novel animal model of pregnancy

The chinchilla as a novel animal model of pregnancy

Current perspectives in avian nutrition: domestic animal models and their role in conservation management

Arsénico, cadmio, mercurio y plomo en alimentos importados para mascotas en Costa Rica

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