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Coordination-Driven Self-Assemblies with a Carborane Backbone

“…Carboranes are highly symmetrical cage cluster molecules that exhibit three-dimensional aromaticity. Their icosahedral structure gives rise to high thermal and chemical stability, and makes them extremely useful building blocks and templates in the design and synthesis of liquid crystalline materials, , rigid molecular rods, − nonlinear optical materials, , and highly stable polymers. − Due to their unique stability, inertness, and hydrophobic character, carboranes are also attractive candidates for use in boron neutron capture therapy (BNCT). − …”

“…[38][39][40][41] Due to their unique stability, inertness, and hydrophobic character, carboranes are also attractive candidates for use in boron neutron capture therapy (BNCT). [42][43][44][45][46][47][48] Incorporating carboranes into supramolecular chemistry has been a long-standing goal, 33,[49][50][51] with the expectation that the supramolecular compounds will have properties in addition to those of the parent carborane molecules. 52,53 There are numerous examples of organic [49][50][51]54 and mercuracarborand macrocycles; 52,53,55 however, they require multistep and/or low-yield synthetic procedures.…”

Synthesis and Structural Characterization of Carborane-Containing Neutral, Self-Assembled Pt-Metallacycles

“…The acidity of the terminal C−H bonds and the specific reactivity of the B−H groups in these boron clusters can be used to selectively functionalize both vertices, thereby generating a series of building blocks to be used in the synthesis of various kinds of supramolecular materials. There have been numerous examples where carborane units have been used for the synthesis of liquid crystalline materials, , catalysts, highly stable polymers, − nonlinear optical materials, , pharmaceuticals (for boron capture neutron therapy), − and rigid molecular rods (for nanoarchitecture). − It has also been shown that carborane cages are capable of transmitting “electronic” information between two Co 2 C 2 tetrahedral clusters . Grimes and co-workers described the synthesis of a “planar octagonal cobaltacarborane” and studied its electrochemical properties .…”

Boronated DNA-Binding Compounds as Potential Agents for Boron Neutron Capture Therapy

“…phthalocyanines, have been reported [9,[65][66][67] and their propensity to accrete within tumour cells at very high levels is very well known. phthalocyanines, have been reported [9,[65][66][67] and their propensity to accrete within tumour cells at very high levels is very well known.…”