R056: Role of PTH in Predicting Hypocalcemia after Thyroidectomy

Abstract

strand cDNAs. SERPINB11 mRNA level were quantified by real-time PCR in HNSCC cells. RESULTS: Four SERPINB11 clones encoded for a fulllength serpin containing 8 exons and harbored polymorphisms in key structural elements. SERPINB11 mRNA is expressed in squamous cell epithelial cell line, HaCaT, and is significantly down-regulated in HNSCC cell lines. CONCLUSION: SERPINB11 is a novel clade B serpin that is expressed in squamous epithelium and is down-regulated in HNSCC cells. SIGNIFICANCE: Loss of expression of SERPINB11 may play a role in the malignant progression of HNSCC.