R and Bioconductor Packages in Bioinformatics: Towards Systems Biology

Genetic determinants of low vitamin B12 levels in Alzheimer's disease risk

“…We verified that each selected SNP was also reported in the Alzheimer's study, was not associated with Alzheimer's (either in the Alzheimer's disease meta-analysis or through a PubMed search of the variant rsID) to circumvent possible pleiotropic effects. We conducted an inverse weighting Mendelian randomization [17] as our primary analysis using the MendelianRandomization and metafor packages in R version 3.5.0 ( http://www.r-project.org/ ) [18] .…”