Trajectory tracking is one of the key technologies for high-precision agriculture and has been the research focus by a large number of academics. In order to design a simple trajectory tracking control scheme, an adaptive sliding mode control based on lateral deviation is proposed. To reduce the chattering phenomenon, an adjustable parameter associated with the sliding surface and system error is introduced, by which the forward gain value can be regulated with the state change. According to the established tractor model, the desired front wheel angle can be obtained as the output of the sliding mode controller. A modified Smith predictor structure based two degree of freedom control scheme is designed to follow the desired front wheel angle. The effectiveness of the designed trajectory tracking control system is demonstrated by simulations, especially the performance of preventing chattering phenomenon.