Quinazolines

Crystal Structure of 2-[2-hydroxy-3-methoxyphenyl]-3-[2-hydroxy-3-methoxybenzylamino]-1,2-dihydroquinazolin-4(3H)-one and the Synthesis, Spectral and Thermal Investigation of its Transition Metal Complexes

“…The electronic spectrum of the cobalt(II) complex shows two bands at 15,873 and 19,230 cm )1 which are assigned to 4 T 1g fi 4 A 2g (F) (m 2 )and 4 T 1g (F) fi 4 T 1g (P) (m 3 ) transitions, respectively, expected for an octahedral cobalt(II) complex [22]. The electronic spectrum of the nickel(II) complex exhibits three bands at 10,000, 14,880 and 23,529 cm )1 , attributable to 3 A 2g (F) fi 3 T 2g (F) (m 1 ), 3 A 2g (F) fi 3 T 1g (F) (m 2 )and 3 A 2g (F) fi 3 T 1g (P) (m 3 ) transitions, respectively, expected for an octahedral nickel(II) complex [19]. The manganese(II), zinc(II) and cadmium(II) complexes did not show any d-d bands.…”

“…Quinazolin-4(3H)-ones are of interest as potential bioactive molecules [1][2][3]. A variety of pharmacological activities are exhibited by quinazolinone derivatives [4][5][6], for example, 2-methyl-3-(o-tolyl)quinazolin-4(3H)-one (methaqualone) (R = CH 3 ) and 2-methyl-3-(o-chlorophenyl)quinazolin-4(3H)-one (meclaqualone) (R = Cl), have been used as hypnotic, sedative and anticonvulsive drugs [7,8].…”

Screening of Five and Six-Membered Nitrogen-Containing Heterocyclic Compounds as New Effective Stimulants of Linum Usitatissimum L. Organogenesis in Vitro

“…The another strategic focus of our researches is study the influence of low molecular weight heterocyclic compounds derivatives of classes pyridine, pyrimidine, pyrazole and isoflavones on the plant growth and development with the prospect of their using as effective substitutes of traditional plant growth regulators in the biotechnological practice. In favor of target area of our researches witness numerous studies conducted by another authors [43][44][45][46][47][48][49][50][51][52][53].…”

Design, synthesis and potential CNS activity of some novel 1-(4-substituted-phenyl)-3-(4-oxo-2-propyl-4H-quinazolin-3-yl)-urea

“…One of the most frequently encountered heterocyclic compound in medicinal chemistry is 4(3H)-quinazolinone with wide applications including antibacterial, antifungal, anticonvulsant, antiinflammatory activities [1][2][3][4] . A literature survey revealed that the presence of a substituted aromatic ring at position 3 and a methyl group at position 2 are a necessary requirement for central nervous system (CNS) depression and anticonvulsant activities.…”