Quiescence of Asian dust events in South Korea and Japan during 2012 spring: Dust outbreaks and transports

Lee, Yun Gon; Ho, Chin Siong; Kim, Joo Hong; Kim, Jhoon

doi:10.1016/j.atmosenv.2015.05.035

Cited by 30 publications

(27 citation statements)

References 39 publications

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“…FD particles have become a major cause of air pollution in several parts of the world, mainly eastern China, Korea, and Japan due to the marked upsurge in industrialization, coal-burning power plants, vehicular traffic, heavy mining operations, sand storms, and other anthropogenic and natural events (Lee et al 2015c). Although FD has become a major issue in the Southeast Asian region, only a few studies describe their size or chemical composition.…”

Section: Discussionmentioning

confidence: 99%

“…They are primarily composed of oxides and carbonates of metals abundant in the soil. During spring, dust storms originating in Siberia and Mongolia carry the dust particles southeastward via strong northwesterlies, leading to the accumulation the dust particles mainly in low-pressure areas such as eastern China, Korea, and Japan (Lee et al 2015c). In addition to natural sources, anthropogenic activities such as heavy mining operations, constructions, and a host of other activities that disturb the environmental balance, have indirectly contributed to the release of mineral dust into the atmosphere.…”

Section: Chemicals and Reagentsmentioning

confidence: 99%

“…Air pollution due to fine dust (FD) particles has recently become a subject of increasing concern in many parts of the world including eastern China, Korea, and Japan with detrimental effects on humans and other organisms. Rapid advances in industrialization, increased usage of petroleum-powered vehicles, heavy mining operations, coal-burning power plants and a host of other anthropogenic activities have greatly contributed to air pollution, they continue to adversely affect the environment and human health (Lee et al 2015c). Air pollutants could include any toxic gas or airborne particle having an aerodynamic diameter less than 10 μm.…”

Section: Introductionmentioning

confidence: 99%

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Inhibition of inflammatory responses elicited by urban fine dust particles in keratinocytes and macrophages by diphlorethohydroxycarmalol isolated from a brown alga Ishige okamurae

Fernando¹,

Kim²,

Sanjeewa³

et al. 2017

ALGAE

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Fine dust (FD) particles have become a major contributor to air pollution causing detrimental effects on the respiratory system and skin. Although some studies have investigated the effects of FD on the respiratory system, their possible effects on the skin remain under-explored. We investigated the FD mediated inflammatory responses in keratinocytes, present in the outer layers of skin tissues and the transfer of inflammatory potential to macrophages. We further evaluated the anti-inflammatory effects of the polyphenolic derivative, diphlorethohydroxycarmalol (DPHC) isolated from Ishige okamurae against FD-induced inflammation. Size distribution of FD particles was analyzed by scanning electron microscopy. FD particles induced the production of cyclooxygenase-2, prostaglandin E2 (PGE 2), interleukin (IL)-1β, and IL-6 in HaCaT keratinocytes and the expression of nitric oxide (NO), inducible nitric oxide synthases (iNOS), PGE 2 , tumor necrosis factor-α expression in RAW 264.7 macrophages. Further, we evaluated the inflammatory potential of the culture medium of inflammation-induced HaCaT cells in RAW 264.7 macrophages and observed a marked increase in the expression of NO, iNOS, PGE 2 , and proinflammatory cytokines. DPHC treatment markedly attenuated the inflammatory responses, indicating its effectiveness in suppressing a broad range of inflammatory responses. It also showed antiinflammatory potential in in-vivo experiments using FD-stimulated zebrafish embryos by decreasing NO and reactive oxygen species production, while eventing cell death caused by inflammation.

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Section: Discussionmentioning

confidence: 99%

Section: Chemicals and Reagentsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Inhibition of inflammatory responses elicited by urban fine dust particles in keratinocytes and macrophages by diphlorethohydroxycarmalol isolated from a brown alga Ishige okamurae

Fernando¹,

Kim²,

Sanjeewa³

et al. 2017

ALGAE

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“…We followed the definition of dust events adopted in the regulations of surface meteorological observations of China (CMA, 2004;Wang et al, 2008) and identified dust events based on the meteorological records (Weather Phenomenon) of Qingdao from the Meteorological Information Comprehensive Analysis and Process System (MICAPS) of the China Meteorological Administration. Due to no dust events lasting over 12 h (Lee et al, 2015;Su et al, 2017;, we collected one dust sample with a 4 h duration in a day. The sampling for dust particles started only when the measured PM 10 mass concentration in Qingdao (http://www.qepb.gov.cn/m2/) and the forecasted dust mass over Asia (http://www-cfors.nies.go.jp/~cfors/) had greatly increased.…”

Section: Introductionmentioning

confidence: 99%

The concentration, source and deposition flux of ammonium and nitrate in atmospheric particles during dust events at a coastal site in northern China

Liu

Yao

et al. 2018

Atmos. Chem. Phys.

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Abstract. Asian dust has been reported to carry anthropogenic reactive nitrogen during transport from source areas to the oceans. In this study, we attempted to characterize NH 4 and NO − 3 in each total suspended particle (TSP) sample, the samples can be classified into increasing or decreasing types. In Category 1, the concentrations of NH + 4 and NO − 3 were 20-440 % higher in dust day samples relative to samples collected immediately before or after a dust event. These concentrations decreased by 10-75 % in the dust day samples in Categories 2 and 3. Back trajectory analysis suggested that multiple factors, such as the transport distance prior to the reception site, the mixing layer depth on the transport route and the residence time across highly polluted regions, might affect the concentrations of NH .

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“…Particulate matter have become a major concern owing to their increased level in air pollution correlating with higher respiratory diseases in metropolitan cities of the world, Human health is a challenge due to rapid advancement in cities and urbanization due to emission of hazardous gases from engines of heavy vehicles and burning of fossil fuels and mining (1). Coal burning power plants emit organic pollutants including polycyclic aromatic hydrocarbons, benzene, toluene and multitude of different gases.…”

Section: Introductionmentioning

confidence: 99%

Recapitulation of Particulate matter Effected Human Alveolus on Chip Inflammatory Responses

Jabbar

Kim

Soomro

et al. 2020

Preprint

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Background Particulate matter (PM10) pollution around the globe is a major risk factor for inducing respiratory diseases, How-ever such environmental conditions are a challenge to study in trans-well culture system. Micro-physiological system offers potential for mimicking these phenomena for better understanding of possible hazards to human respiratory health. In this study we are introducing an efficient alveolus on a chip for reconstituting this environmental condition in a microfluidic device by in house built TEER sensor, system embedded pH sensor and portable microscope for continuous monitoring of the alveolus on chip. Results Three environmental conditions with respect to particulate matter in air Moderate 7.5 μg/ml , Poor 37.5 μg/ml and very poor 151 μg/ml of particulate matter exposure was executed in our microfluidic system. Our study provides physiological and toxicological data of the stimulated environmental condition by inflammatory markers of respiratory disease which leads to the identification of asthma and COPD, our claims were validated by confocal microscopy and ELISA. Significant increase in IL-13, IL-6 and Mucin advocated the incidence of asthma and COPD like conditions in our organ on chip. Conclusion This study will lead to identification of potential therapeutics to study physiological and pathological conditions and will help in preventing chronic life-threatening toxicities. This device has provided the preliminary information for making this breakthrough in organ-on-chip technology. In future his device would help to make complex tissue mimetics of human for toxicity testing and drug discovery with system integrated pathological sensors for replacing time consuming molecular analysis of pathological conditions.

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Quiescence of Asian dust events in South Korea and Japan during 2012 spring: Dust outbreaks and transports

Cited by 30 publications

References 39 publications

Inhibition of inflammatory responses elicited by urban fine dust particles in keratinocytes and macrophages by diphlorethohydroxycarmalol isolated from a brown alga Ishige okamurae

Inhibition of inflammatory responses elicited by urban fine dust particles in keratinocytes and macrophages by diphlorethohydroxycarmalol isolated from a brown alga Ishige okamurae

The concentration, source and deposition flux of ammonium and nitrate in atmospheric particles during dust events at a coastal site in northern China

Recapitulation of Particulate matter Effected Human Alveolus on Chip Inflammatory Responses

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