Questionnaire survey on management of antithrombotic agents during surgery or kinds of medical procedures with bleeding

英一, 石川; 正弘, 矢坂; 靖, 岡田

doi:10.3995/jstroke.35.425

Cited by 4 publications

(2 citation statements)

References 8 publications

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“…It is hypothesized that the sum of patients receiving APT could be as high as 1.2 million in Japan according to an insurance database of antiplatelet agents. 9 Simultaneously, the number of these patients undergoing operations is increasing. Nevertheless, there has been little research on the management of antiplatelet agents during the perioperative period.…”

Section: Discussionmentioning

confidence: 99%

“…Because the aging population in Japan has increased in recent years, the number of patients with circulatory disturbances, such as brain tissue disorders and cardiovascular problems, has also increased. It is hypothesized that the sum of patients receiving APT could be as high as 1.2 million in Japan according to an insurance database of antiplatelet agents 9 . Simultaneously, the number of these patients undergoing operations is increasing.…”

Section: Discussionmentioning

confidence: 99%

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The effect of antiplatelet therapy on outcomes in patients who underwent laparoscopic radical nephrectomy: A Japanese single‐center study

Nakayama

Sakano

Shinohara

et al. 2023

Asian J Endoscop Surgery

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ObjectivesThe number of patients receiving antiplatelet therapy (APT) who have undergone laparoscopic radical nephrectomy is increasing. However, it is unclear whether APT affects the outcomes of patients undergoing radical nephrectomy. We investigated the perioperative outcomes of radical nephrectomy in patients with and without APT.MethodsWe retrospectively collected data from 89 Japanese patients who underwent laparoscopic radical nephrectomy for clinically diagnosed renal cell carcinoma (RCC) at Kokura Memorial Hospital between March 2013 and March 2022. We analyzed information related to APT. We divided the patients into two groups: the APT group (patients receiving APT) and the N‐APT group (patients not receiving APT). Moreover, the APT group was further divided into the C‐APT group (patients with continuous APT) and the I‐APT group (patients with interrupted APT). We compared the surgical outcomes of these groups.ResultsAmong 89 patients eligible for the study, 25 received APT and 10 continued APT. Even though the patients who received APT had a high American Society of Anesthesiologists physical status and many complications, including smoking, diabetes, hypertension, and chronic heart failure, no significant difference in the intra‐ or postoperative outcomes, including bleeding complications, was observed regardless of whether the patients received APT or continued APT.ConclusionsWe concluded that in laparoscopic radical nephrectomy, continuation of APT is an acceptable strategy for patients with thromboembolic risk caused by interruption of APT.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

The effect of antiplatelet therapy on outcomes in patients who underwent laparoscopic radical nephrectomy: A Japanese single‐center study

Nakayama

Sakano

Shinohara

et al. 2023

Asian J Endoscop Surgery

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Effect of discontinuing antithrombotic drugs in patients undergoing percutaneous endoscopic gastrostomy

Narita¹,

Murase²,

Yoneda³

et al. 2019

Prog. dig. Endosc

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Safety and Management of Antithrombotic Therapy with Intra-Arterial Catheter Procedures

et al. 2015

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Objective Intravascular catheter procedures are often performed in patients undergoing antithrombotic therapy. However, methods for the management of antithrombotic agents in the perioperative period are currently unclear. Therefore, the safety and management of antithrombotic agents in these patients were investigated. Methods A prospective, multicenter, observational study [Management of Antithrombotic Agents During Surgery or Medical Procedures with Bleeding (MARK study)] at 58 National Hospital Organization institutions in Japan was performed. 1,040 patients were enrolled in the MARK study and underwent an intravascular catheter procedure. For all participants, the details of the procedure, method of perioperative management of antithrombotic agents, and occurrence of thrombosis, embolism, and bleeding complications during the study period were investigated. Results The use of antithrombotic agents was continued in 1,017 patients (98%, continuation group) and discontinued in the other 23 (2%, discontinuation group). Continuation of the antithrombotic agents did not have a significant effect on the overall occurrence of thromboembolism [hazard ratio (HR), 0.15; p=0.08] or bleeding events (HR, 0.19; p=0.12). However, the overall adverse event risk was significantly lower in the continuation group than in the discontinuation group (HR, 0.18; p=0.03). Conclusion It is both safe and appropriate to perform intravascular catheter procedures in patients continuing with antithrombotic therapy.

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Questionnaire survey on management of antithrombotic agents during surgery or kinds of medical procedures with bleeding

Cited by 4 publications

References 8 publications

The effect of antiplatelet therapy on outcomes in patients who underwent laparoscopic radical nephrectomy: A Japanese single‐center study

The effect of antiplatelet therapy on outcomes in patients who underwent laparoscopic radical nephrectomy: A Japanese single‐center study

Effect of discontinuing antithrombotic drugs in patients undergoing percutaneous endoscopic gastrostomy

Safety and Management of Antithrombotic Therapy with Intra-Arterial Catheter Procedures

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