Quercetagetin-Stabilized Silver Nanoparticles for the Oxidation of Morin

Abstract

Herein, we present a facile and convenient method for the preparation of silver nanoparticles (AgNPs) in the presence of quercetagetin, a unique plant flavonoid, as a reducing and stabilizing agent. The nanoparticles (Que-AgNPs) were characterized using UV–vis spectroscopy, transmission electron microscopy, energy-dispersive X-ray spectroscopy, X-ray diffraction, and dynamic light scattering techniques. Que-AgNPs display a spherical shape and a crystalline structure. The size of Que-AgNPs was calculated to be 93 ± 0.4 nm in diameter with polydispersity index value of 0.3. Que-AgNPs were evaluated as nanocatalysts in the oxidative degradation of morin with hydrogen peroxide (H2O2). The catalytic degradation of morin was completed within 20 min, demonstrating excellent catalytic properties for Que-AgNPs. Kinetic studies revealed that the reaction follows pseudo-first-order kinetics and the apparent rate constant (k app) is positively correlated with the concentration of Que-AgNPs; however, k app is inversely associated with the morin concentration. Moreover, the cytotoxicity of Que-AgNPs was evaluated by the cell viability test considering two cell lines, i.e., HeLa and MCF-7. The results show that Que-AgNPs possess dose-dependent cytotoxic activity.

Catalytic investigation of hyaluronic acid-stabilized Ag nanoparticles as non-toxic nanocatalysts in the oxidation of morin

“…04-0783 and the results confirm that HA-AgNPs are highly crystalline silver nanoparticles with a face-centered-cubic (fcc) structure. 24 The surface functionalization of AgNPs by hyaluronic acid was further characterized by FTIR analyses (Fig. S2, ESI †).…”

“…04–0783 and the results confirm that HA-AgNPs are highly crystalline silver nanoparticles with a face-centered-cubic (fcc) structure. 24…”

“…22,23 Following this study, a facile in-situ preparation of AgNPs with quercetagetin (6-hydroxyquercetin), a plant flavonol, used as a stabilizing material and their catalytic activity in the degradation of morin with H 2 O 2 was recently reported by our research group. 24 However, the toxic effects of PAMAM-and Que-coated AgNPs should be seriously considered; 24,25 that is, the reports on nontoxic and efficient AgNP-based oxidation nanocatalysts are still limited.…”

Molecular Nanotechnology for Tomorrow’s World: A Forum Dedicated to Professor Sir Fraser Stoddart on the Occasion of His 80th Birthday

“…30 Bulut and Yilmaz reported quercetagetin-integrated silver nanoparticles for morin oxidation, affording dosedependent cytotoxicity to selected cell lines. 31 Bruns and coworkers prepared diarylethene-doped polystyrene nanoparticles as photochromic intradermal tattoos for applications in personal γ-ray dosimetry. 32 Wang et al comprehensively reviewed recent developments of nanoporous covalent organic frameworks for bioimaging, drug delivery, phototherapy, and antibacterial applications.…”

“…Yang and co-workers found enhanced luminescence and self-driven gelation from a pyrene-modified pillar[5]­arene nanostructure for potential imaging applications . Bulut and Yilmaz reported quercetagetin-integrated silver nanoparticles for morin oxidation, affording dose-dependent cytotoxicity to selected cell lines . Bruns and co-workers prepared diarylethene-doped polystyrene nanoparticles as photochromic intradermal tattoos for applications in personal γ-ray dosimetry .…”