Quelle chance que le patient soit médecin!

Lercanidipine-induced chylous ascites: Case report and literature review

“…[2][3][4][5][6][7][8] We describe a rare case of chylous ascites and constitutional syndrome suggestive of hidden malignancy that after a thorough research, no apparent cause was detected. It develops when there is a disruption of the lymphatic system due to traumatic injury or obstruction.…”

“…Most were associated with lercanidipine. [3][4][5] This adverse effect had also been described in patients with microscopic polyangeitis 7 and systemic lupus erythematosus, 8 need for in vitro models that explore the interactions between different types of CCB and the smooth muscle in lymphatic vessels, as well as larger randomized trials, to try to find out the real impact and the relationship between different CCB and chylous ascites.…”

“…1 There have been few previous reports of calcium channel blockers (CCB) as potential causes of this entity. [2][3][4][5][6][7][8] We describe a rare case of chylous ascites and constitutional syndrome suggestive of hidden malignancy that after a thorough research, no apparent cause was detected. Finally, as there was a dose-related effect, and the most frequent causes were discarded, lercanidipine was identified as the aetiology of this rare condition.…”