“…The current RCT detection methods include electrochemical and fluorescence detection (Liu, Chen, et al, 2011;Liu, Lin, et al, 2011;Rajkumar, Li, & Chen, 2013;Wang, Yong, He, Du, Ma, Dan, et al, 2013), gas chromatography (Fang et al, 2011), liquid chromatography-mass spectrometry (Amelin, Korolev, & Tret'yakov, 2015;Dong, Xi, Xia, Ding, Li, Zhang, et al, 2011;Liu, Yan, & Zhang, 2014;Liu, Ning, Qu, Peng, Dong, Gao, et al, 2012;Wei et al, 2014), ultra-performance liquid chromatography-tandem mass spectrometry (Jing-Kai, Teh-Ia, Lie-Chwen, & Tung-Hu, 2014), high-performance liquid chromatography (Li, Zhang, Deng, Yang, Liu, Xiao, et al, 2010), capillary electrophoresis (Anurukvorakun, Buchberger, Himmelsbach, Klampel, & Suntornsuk, 2010), and immunoassays (Cao et al, 2013;Mei, Xue, Chao, Bo, Wen, Heng Yi, et al, 2014;Sairi & Arrigan, 2015). Even though these methods are very sensitive, they require complex and time-consuming pretreatment steps and the instruments are costly.…”