Quaternization of N‐Heterocycles with Propylene Oxide and Epichlorohydrin.

Abstract

Quaternization of N-Heterocycles with Propylene Oxide and Epichlorohydrin. -Heterocyclic N-2-hydroxypropyl and N-2-hydroxy-3-chloropropyl quaternary salts [(III), (V), (VIII) and (X)] are prepared by reaction of propylene oxide (II) or epichlorohydrin (VII), resp., with the appropriate bases. -(VASSILEV, A.; DIKOVA, I.; DELIGEORGIEV*, T.; DREXHAGE, K.-H.; Synth.