The preceding papers (1) in this series have shown that chloroform produces similar effects on the rate of production of CO, by living and killed tissue and by unsaturated organic acids. In the case of dead tissue and organic acids, the system consisted of oxidizable material, H202 and Fe2(SO4)3. The experimental results indicate that similar processes are taking place in all cases. In this paper an attempt is made to verify this statement and to show that a mathematical interpretation of the curves indicates that the reactions are all of the same order.There are certain considerations that must be taken into account in order to derive a formula which will approximate the conditions found experimentally. It is necessary to assume that there is present in the reaction mixture, before the addition of chloroform, a complex consisting of two, or possibly three, of the components of the reaction. It is plausible to assume that this condition exists in the reaction, for it is quite evident that here we have to deal with an "induced reaction." Mellor (2), in discussing this type of reaction, points out that it may be considered as taking place in two ways; either that the reaction is catalyzed by the presence of the third reacting substance, which may mean the formation of a complex, or that two (or possibly three) of the constituents of the reaction combine.In the case which we are discussing--oxidation by means of H202 and Fe~(SO4)8--we consider that the complex is being broken down at a constant rate, with a production of CO2 directly proportional to the rate of decomposition of the complex. We assume that the reaction starts from a substance, A, which in turn goes into the com-