“…O,O-Demethylenated benzo[c]phenanthridine, protoberberine, and protopine alkaloids have been detected as minor alkaloids in several members of the Papaveraceae, including Fummaria vaillantii (45), Macleaya cordata (46), and Thalictrum javanicum (47). Previously, the detection of O,O-demethylenated BIAs was suggested as an artifact of extraction processes, although their natural occurrence could not be discounted (46).…”