Quantum dynamical maps are defined and studied for quantum statistical physics based on Orlicz spaces. This complements earlier work [46] where we made a strong case for the assertion that statistical physics of regular systems should properly be based on the pair of Orlicz spaces L cosh −1 , L log(L + 1) . The present paper therefore in some sense "completes" the picture by showing that even in the most general non-commutative contexts, completely positive Markov maps satisfying a natural Detailed Balance condition, canonically admit an action on a large class of quantum Orlicz spaces. This is achieved by the development of a new interpolation technique, specifically suited to the above context, for extending the action of such maps to the appropriate intermediate spaces of the pair L ∞ , L 1 . Moreover, it is shown that quantum dynamics in the form of Markov semigroups described by some Dirichlet forms naturally extends to the context proposed in [46].