In this work we propose a quantum version of a generalized Monty Hall game, that is, one in which the parameters of the game are left free, and not fixed on its regular values. The developed quantum scheme is then used to study the expected payoff of the player, using both a separable and an entangled initial-state. In the two cases, the classical mixed-strategy payoff is recovered under certain conditions. Lastly, we extend our quantum scheme to include multiple independent players, and use this extension to sketch two possible application of the game mechanics to quantum networks, specifically, two validated, mult-party, key-distribution, quantum protocols.