Quantum Dots as Biosensors in the Determination of Biochemical Parameters in Xenobiotic Exposure and Toxins

Ravi, Poorvisha; Ganesan, Muthupandian

doi:10.2116/analsci.20scr03

Cited by 8 publications

(2 citation statements)

References 134 publications

(55 reference statements)

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“…The unique optical properties of QDs make QDs incorporated into the biosensor systems to integrate selectivity, efficiency, accuracy, and high detection sensitivity into a single system [35]. The biosensors containing QDs show their potential in various areas, such as diagnostic, toxicological, and follow-up medical applications [36,37]. With these features, QDs have been used for new methods for the identification of biologically relevant molecules recently [38].…”

Section: Qds In Biosensorsmentioning

confidence: 99%

Quantum dots and their potential biomedical applications

2024

ACE

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Quantum dots (QDs) are semiconductor-based nanocrystals. These nanoparticles have exhibited their unique optical and electronic properties. With these characteristics, QDs attracted scientists interest in biomedical areas such as bioimaging, drug delivery and biosensors apart from other applications like photocatalysis, light-emitting, and solar cells in recent years, and plenty of QDs and QD-based materials have exhibited their unique properties in their applications of biomedical areas. Nevertheless, the potential toxicity of QDs becomes the limitation of QDs application in biomedical areas. The toxicity of QDs might come from: the toxicity core material of QDs; the toxicity substances from the surface of QDs; the free radicals or reactive species released from QDs; the biological environment induced QDs toxicity. In this article, we review the properties of QDs, the applications of QDs in different biomedical fields, how QDs cause toxicity, and how to reduce or prevent QDs potential toxicity. In the future, we expect the improvement and further application of QDs in biomedical areas.

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Section: Qds In Biosensorsmentioning

confidence: 99%

Quantum dots and their potential biomedical applications

2024

ACE

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“…International Journal of Nanomedicine 2022:17 1958 diagnostic, toxicological, and follow-up medical applications. 73,74 In addition, QDs-based sensors have been applied extensively in environmental applications such as detection of water and soil contamination, which are beyond the scope of the current article. 75 In the area of vital biochemical markers, Shen and Xia synthesized carbon QDs (CQDs) modified with boronic acid moieties as biosensors for the measurement of the blood glucose level.…”

Section: Dovepressmentioning

confidence: 99%

Biomedical Applications of Quantum Dots: Overview, Challenges, and Clinical Potential

Abdellatif¹,

Younis²,

Alsharidah³

et al. 2022

IJN

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Despite the massive advancements in the nanomedicines and their associated research, their translation into clinicallyapplicable products is still below promises. The latter fact necessitates an in-depth evaluation of the current nanomedicines from a clinical perspective to cope with the challenges hampering their clinical potential. Quantum dots (QDs) are semiconductors-based nanomaterials with numerous biomedical applications such as drug delivery, live imaging, and medical diagnosis, in addition to other applications beyond medicine such as in solar cells. Nevertheless, the power of QDs is still underestimated in clinics. In the current article, we review the status of QDs in literature, their preparation, characterization, and biomedical applications. In addition, the market status and the ongoing clinical trials recruiting QDs are highlighted, with a special focus on the challenges limiting the clinical translation of QDs. Moreover, QDs are technically compared to other commercially-available substitutes. Eventually, we inspire the technical aspects that should be considered to improve the clinical fate of QDs.

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