Quantum defects as versatile anchors for carbon nanotube functionalization

Mann, Florian A.; Galonska, Phillip; Herrmann, Niklas; Kruss, Sebastian

doi:10.1038/s41596-021-00663-6

Cited by 30 publications

(31 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, to obtain a more complete picture, further studies comparing different surface modifications with enantiomers of various SWCNT chiralities would be needed. Well-defined monochiral SWCNTs exhibit noncongested emission spectra, which makes them favorable for a covalent incorporation of quantum defects because the related new emission features (E 11 *) can be clearly distinguished. − Defects can be also used for sensing of, for example, pH or temperature . Another example are sensors for the neurotransmitter dopamine that use DNA-coated SWCNTs with quantum defects .…”

Section: General Aspects and Examples Of Monochiral Sensorsmentioning

confidence: 99%

“…In principle, such sensors are freely tunable in emission wavelengths over a wide wavelength range between ∼800 and 1700 nm (by choosing the appropriate SWCNT chirality) and analyte specificity (by changing the surface modification). Besides the already discussed impact of noncovalent surface modification, recent progress in covalent modification approaches will extend the range of accessible emission colors, ,,, functional handles, , and sensing capabilities. ,, However, to reach such powerful analytical tools, several obstacles had to be solved, as discussed above. The way to such sensors is highly interdisciplinary, combining separation science and covalent as well as noncovalent surface chemistry with multispectral optical detection and imaging.…”

Section: Challenges and Outlookmentioning

confidence: 99%

See 1 more Smart Citation

Prospects of Fluorescent Single-Chirality Carbon Nanotube-Based Biosensors

Nißler

Ackermann

et al. 2022

Anal. Chem.

Self Cite

View full text Add to dashboard Cite

Semiconducting single-wall carbon nanotubes (SWCNTs) fluoresce in the near-infrared (NIR), and the emission wavelength depends on their structure (chirality). Interactions with other molecules affect their fluorescence, which has successfully been used for SWCNT-based molecular sensors. So far, most such sensors are assembled from crude mixtures of different SWCNT chiralities, which causes polydisperse sensor responses as well as spectral congestion and limits their performance. The advent of chirality-pure SWCNTs is about to overcome this limitation and paves the way for the next generation of biosensors. Here, we discuss the first examples of chirality-pure SWCNT-based fluorescent biosensors. We introduce routes to such sensors via aqueous two-phase extraction-assisted purification of SWCNTs and highlight the critical interplay between purification and surface modification procedures. Applications include the NIR detection and imaging of neurotransmitters, reactive oxygen species, lipids, bacterial motives, and plant metabolites. Most importantly, we outline a path toward how such monodisperse (chirality-pure) sensors will enable advanced multiplexed sensing with enhanced bioanalytical performance.

show abstract

Section: General Aspects and Examples Of Monochiral Sensorsmentioning

confidence: 99%

Section: Challenges and Outlookmentioning

confidence: 99%

Prospects of Fluorescent Single-Chirality Carbon Nanotube-Based Biosensors

Nißler

Ackermann

et al. 2022

Anal. Chem.

Self Cite

View full text Add to dashboard Cite

show abstract

“…In terms of material doping, the incorporation of defect states could perhaps lead to novel properties similar to quantum defects in SWCNTs. [122][123][124] Moreover, tailoring of surface chemistry is a crucial step to improve water solubility and allow targeting of molecules of interest, as required for e.g. drug delivery and image-guided surgery.…”

Section: Discussionmentioning

confidence: 99%

Preparation, properties and applications of near-infrared fluorescent silicate nanosheets

Selvaggio

Kruss

2022

Nanoscale

Self Cite

View full text Add to dashboard Cite

show abstract

“…As a final 49,56 . A key to all these applications is versatile non-covalent and recently covalent surface chemistry 53,94,95 . It enabled imaging of neurotransmitters 96-100 , reactive oxygen species [101][102][103][104][105][106][107] , polyphenols 108 , disease markers 33,53,109,110 and many other important analytes and biological targets.…”

Section: Discussionmentioning

confidence: 99%

Covalently Functionalized Egyptian Blue Nanosheets for Near-Infrared Bioimaging

Selvaggio

Herrmann

Hill

et al. 2022

Preprint

Self Cite

View full text Add to dashboard Cite

Fluorophores emitting in the near-infrared (NIR) wavelength region present optimal characteristics for photonics and especially bioimaging. Unfortunately, only few NIR fluorescent materials are known and even fewer are biocompatible. For this reason, the scientific interest in designing novel NIR fluorophores is very high. Egyptian Blue (CaCuSi4O10, EB) is a NIR fluorescent layered silicate that can be exfoliated into fluorescent nanosheets (EB-NS). So far, its surface chemistry has not been tailored but this is crucial for colloidal stability and biological targeting. Here, we demonstrate covalent surface functionalization of EB nanosheets (EBfunc) via Si-H activation using hydrosilanes with variable functionalities. EB-NS were first grafted with the visible fluorescent pyrene (Pyr) moieties to prove conjugation by colocalization of the Vis/NIR fluorescence on the (single) EB-NS level. The same procedure was performed and validated with carboxyl group (COOH)-containing hydrosilanes. These groups can serve as generic handle for further (bio)functionalization of the EB-NS surface. Finally, folic acid (FA) was conjugated to these COOH-functionalized EB-NS to target folic acid receptor-expressing cancer cells. These results highlight the potential of this surface chemistry approach to modify EB-NS and enable targeted NIR imaging for biomedical applications.

show abstract

Quantum defects as versatile anchors for carbon nanotube functionalization

Cited by 30 publications

References 56 publications

Prospects of Fluorescent Single-Chirality Carbon Nanotube-Based Biosensors

Prospects of Fluorescent Single-Chirality Carbon Nanotube-Based Biosensors

Preparation, properties and applications of near-infrared fluorescent silicate nanosheets

Covalently Functionalized Egyptian Blue Nanosheets for Near-Infrared Bioimaging

Contact Info

Product

Resources

About