Quantum chemical simulation of the interaction of epirubicin with a fullerene and a carbon graphene-like plane
E.M. Demianenko,
O.V. Khora,
B.M. Gorelov
et al.
Abstract:Creation of new "targeted delivery" drugs is one of the priority areas of pharmacology. This is especially true for oncology. Medicinal substances, in particular of the anthracycline series, immobilized on the surface of nanosized carriers for the targeted delivery of drugs to target organs or target tissues, allow creating an optimal concentration of the drug in the area of therapeutic effect. The latter significantly reduces systemic toxicity by reducing the total dose and longer retention in the lesion, as … Show more
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