The thermodynamic parameters of the formation of monomers, dimers, trimers, tetramers, and one hexamer of alkylamines with the alkyl chain length in the range of 6 to 16 carbon atoms are calculated using the semiempirical PM3 method. The dependencies of potential energy surfaces of monomers and dimers on corresponding torsion angles are analyzed to determine the most stable conformations (local and global minima) of these entities. The thermodynamic parameters of cluster formation (enthalpies, entropies, and Gibbs' energies) are calculated for the dimers, trimers, tetramers, and the hexamer. The additive approach was further developed to extend the results of the calculations of the thermodynamic properties of small associates (2-6 amine molecules) to infinite clusters. It is shown that these parameter values are stepwise-dependent on the alkyl chain length, and spontaneous cluster formation takes place for this class of compounds when the alkyl chain length becomes 18-19 carbon atoms and higher.