This work is the first to determine that a real quantum computer (including generalized and specialized) can decipher million-scale RSA relying solely on quantum algorithms, showing the real attack potential of D-Wave machines. The influence of different column widths on RSA factorization results is studied on the basis of a multiplication table, and the optimal column method is determined by traversal experiments.The traversal experiment of integer factorization within 10 000 shows that the local field and coupling coefficients are 75%-93% lower than the research of Shanghai University in 2020 and more than 85% lower than that of Purdue University in 2018. Extremely low Ising model parameters are crucial to reducing the hardware requirements, prompting factoring 1 245 407 on the D-Wave 2000Q real machine. D-Wave advantage already has more than 5000 qubits and will be expanded to 7000 qubits during 2023-2024, with remarkable improvements in decoherence and topology. This machine is expected to promote the solution of large-scale combinatorial optimization problems. One of the contributions of this paper is the discussion of the long-term impact of D-Wave on the development of post-quantum cryptography standards.