Second-order topological insulators are crystalline insulators with a gapped bulk and gapped crystalline boundaries, but topologically protected gapless states at the intersection of two boundaries. Without further spatial symmetries, five of the ten Altland-Zirnbauer symmetry classes allow for the existence of such second-order topological insulators in two and three dimensions. We show that reflection symmetry can be employed to systematically generate examples of second-order topological insulators and superconductors, although the topologically protected states at corners (in two dimensions) or at crystal edges (in three dimensions) continue to exist if reflection symmetry is broken. A three-dimensional second-order topological insulator with broken time-reversal symmetry shows a Hall conductance quantized in units of e 2 /h.Introduction.-After the discovery of topological insulators and superconductors and their classification for the ten Altland-Zirnbauer symmetry classes [1][2][3], the concept of nontrivial topological band structures has been extended to materials in which the crystal structure is essential for the protection of topological phases [4]. This includes weak topological insulators [5], which rely on the discrete translation symmetry of the crystal lattice, and topological crystalline insulators [6], for which other crystal symmetries are invoked to protect a topological phase. Whereas the original strong topological insulators always have topologically protected boundary states, weak topological insulators or topological crystalline insulators have protected boundary states for selected surfaces/edges only.In a recent publication, Schindler et al. [7] proposed another extension of the topological insulator (TI) family: a higher-order topological insulator. Being crystalline insulators, these have well-defined faces and well-defined edges or corners at the intersections between the faces. An nth order topological insulator has topologically protected gapless states at the intersection of n crystal faces, but is gapped otherwise [7]. For example, a second-order topological insulator in two dimensions (d = 2) has zeroenergy states at corners, but a gapped bulk and no gapless edge states. Earlier examples of higher-order topological insulators and superconductors avant la lettre appeared in works by (see also [11,12]), who considered insulators and superconductors with protected corner states in d = 2 and d = 3 [13]. Sitte et al. showed that a threedimensional topological insulator in a magnetic field of generic direction also acquires the characteristics of a second-order topological Chern insulator, with chiral states moving along the sample edges [14].Since a second-order TI has a topologically trivial d-dimensional bulk, from a topological point of view its boundaries are essentially stand-alone (d − 1)-dimensional insulators, so that topologically protected states at corners (for d = 2) or edges (for d = 3) arise naturally as "domain walls" at the intersection of two boundaries if these ar...