Quantitative susceptibility mapping in the brain reflects spatial expression of genes involved in iron homeostasis and myelination
Zoe Cohen,
Laurance Lau,
Maruf Ahmed
et al.
Abstract:Quantitative susceptibility mapping (QSM) is an MRI modality used to non‐invasively measure iron content in the brain. Iron exhibits a specific anatomically varying pattern of accumulation in the brain across individuals. The highest regions of accumulation are the deep grey nuclei, where iron is stored in paramagnetic molecule ferritin. This form of iron is considered to be what largely contributes to the signal measured by QSM in the deep grey nuclei. It is also known that QSM is affected by diamagnetic myel… Show more
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