“…Therefore, the thirst for the externally predictive QSAR models for the acute toxicity of diverse chemicals towards the D. magna had been continued since many years [5][6][7][8]. In the literature [4,[9][10][11][12], the toxic effects of various hazardous chemicals towards D. magna, have been modeled mainly through the physico-chemical descriptors like octanol/water partition coefficient (log P) representing the hydrophobicity, besides several topological and quantum-chemical descriptors particularly the energy of highest occupied molecular orbital (HOMO) [9].…”