Quantitative salivary gland scintigraphy in the diagnosis of parenchymal damage after treatment with radioiodine

Assessment of Salivary Gland Dysfunction after Radioiodine Therapy for Thyroid Carcinoma Using Non-Contrast-Enhanced CT: The Significance of Changes in Volume and Attenuation of the Glands

“…[5][6][7][8][9]16 In our study, salivary gland scintigraphy showed a dose-dependent salivary dysfunction after RIT, similar to the findings described in previous reports. [5][6][7][8][9] CT examinations of the head and neck are commonly performed during the follow-up period after RIT to screen for recurrence and metastasis. Because iodine contrast material is contraindicated for a few weeks before the RIT, we obtained noncontrast CT images.…”

“…[5][6][7][8][9]16 Several authors have used salivary gland scintigraphy for the assessment of salivary gland dysfunction after RIT and reported a good correlation with the clinical and histopathologic features of the salivary glands. [5][6][7][8][9]16 In our study, salivary gland scintigraphy showed a dose-dependent salivary dysfunction after RIT, similar to the findings described in previous reports. [5][6][7][8][9] CT examinations of the head and neck are commonly performed during the follow-up period after RIT to screen for recurrence and metastasis.…”

“…Generally, qualitative and quantitative salivary gland scintigraphy has been used for the assessment and follow-up of salivary gland dysfunction after RIT. [5][6][7][8][9] CT of the neck and chest is usually performed in patients who have undergone RIT for evaluation of the recurrence and metastasis of thyroid carcinoma. We have noticed that the salivary glands, especially the parotid glands, show some shrinkage and an increase in attenuation on CT scans obtained during the follow-up period after RIT.…”

Obstrução de vias lacrimais associada ao tratamento radioiodoterápico de carcinoma de tireoide

“…É importante salientar o aumento de incidência em todo mundo, sendo que nos EUA observou-se que nos últimos 30 anos houve um aumento de 2,4 vezes, passando de 3,6 para 8,7 casos por 100.000 habitantes (3) . As complicações sistêmicas da RIT geralmente são leves e fugazes, sendo bem estabelecido o acometimento de glândulas salivares com subsequente xerostomia (4,5) . As complicações oculares são pouco relatadas (6) , sendo descritas conjuntivite crônica e recorrente, ceratoconjuntivite seca e xeroftalmia (7) .…”

Current controversies in the initial post-surgical radioactive iodine therapy for thyroid cancer: a narrative review

“…To address this problem, two groups recommend background ROIs outside the mouth. One used the brain (Bohuslavizki et al 1996) and the other used the shoulder (Malpani et al 1996). It is hard to understand as to how these remote sites could represent background activity in the salivary region.…”