Quantitative relationship between end-tidal carbon dioxide and CPR quality during both in-hospital and out-of-hospital cardiac arrest

Cardiopulmonary resuscitation quality and patient survival outcome in cardiac arrest: A systematic review and meta-analysis

“…There were 16 papers from the USA and/or Canada 3,4,6-8,10,12,14,15,25-28,31-33 ; ten of those from centres participating in the ROC. 4,[6][7][8]10,12,14,[26][27][28] Additionally there were six studies from Europe. 1,2,11,13,29,30 The majority of papers featured a cohort design.…”

“…1,2,11,13,29,30 The majority of papers featured a cohort design. 3,4,6,8,[11][12][13][14][25][26][27][28] Six studies were observational. 15,29-33 Four 1,2,7,10 represented a post hoc analysis of data from a trial.…”

“…7 Five papers exclusively examined IHCA, 15,30-33 16 papers examined OHCA 1-4,6-8,10-13,25-29 and one paper examined both IHCA and OHCA cases. 14 …”

“…Quality is commonly defined in terms of parameters such as chest compression depth, compression rate and compression fraction, along with others including ventilation rate, ventilation pause duration, peri-shock pause, duty cycle and incomplete chest release. et al 9 Since the time of that review, a number of papers 3,4,6,7,[10][11][12][13][14][15] have been published, including several large studies 4,7 from the North American Resuscitation Outcomes Consortium (ROC). 16 By incorporating the most recent literature, the present review sought to answer the question of whether a relationship exists between individual CPR quality parameters and patient outcomes from cardiac arrest.…”

A Review of Carbon Dioxide Monitoring During Adult Cardiopulmonary Resuscitation

“…In a recent multicentre cohort study of 583 in-and out-of-hospital cardiac arrests with time-synchronised ETCO 2 and CPR performance data, ETCO 2 values generated during CPR were statistically associated with compression depth [35]. In this study, case-averaged ETCO 2 values in patients with ROSC were higher compared to those who did not have a pulse restored (34.5AE4.5 vs 23.1AE12.9 mmHg, p<0.001).…”