2020
DOI: 10.21203/rs.3.rs-15527/v2
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

Quantitative proteomic analysis of Rett iPSC-derived neuronal progenitors

Abstract: Background Rett syndrome (RTT) is a progressive neurodevelopmental disease that is characterized by abnormalities in cognitive, social and motor skills. RTT is often caused by mutations in the X-linked gene encoding methyl-CpG binding protein 2 (MeCP2). The mechanism by which impaired MeCP2 induces the pathological abnormalities in the brain is not understood. Both patients and mouse models have shown abnormalities at molecular and cellular level before typical RTT-associated symptoms appear. This implies that… Show more

Help me understand this report
View published versions

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 45 publications
(53 reference statements)
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?