Quantitative morphology of the primate peripheral retina (<i>Macaca irus</i>)

Krebs, Wolf; Krebs, Ingeborg

doi:10.1002/aja.1001790212

Cited by 23 publications

(19 citation statements)

References 17 publications

(13 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is apparent by comparison of Figure 2 with Figure 1 of our previous article (Krebs and Krebs, 1987) which depicts the pigment epithelium of the same retina at the same magnification but at 30" eccentricity. The height of pigment epithelial cells is increased in the fovea (Polyak, 1941) so that their volume may remain constant throughout the retina.…”

Section: Cones and Pigment Epitheliummentioning

confidence: 73%

“…9; see also Figs. 5 and 6 in Krebs and Krebs, 1987). The density of all of these profiles was equivalent to the density of bipolar cells.…”

Section: Resultsmentioning

confidence: 99%

“…The density of bipolar cells in the peripheral retinas of monkeys 2 and 3 was close to 50,000/mm2 and the cone cell density was 8,200/mm2 (Krebs and Krebs, 1987). If cone mediated vision does not vary with the location of the cone cell within the retina, one peripheral cone cell will be contacted by about 2.5 bipolar cells.…”

Section: The Neurons Of the Inner Retinamentioning

confidence: 99%

See 2 more Smart Citations

Quantitative morphology of the central fovea in the primate retina

Krebs

1989

Am. J. Anat.

Self Cite

View full text Add to dashboard Cite

Electron micrograph composites of tangenital sections of the fovea centralis of three cynomolgus monkeys (Macaca irus) and one baboon (Papio anubis) were used to determine the spatial density of the principal retinal cells. In the center of the foveola, the density of cones ranged from 113,000 to 230,000/mm2, and pigment epithelial cells from 4,900 to 7,000/mm2. At a distance of 500 microns from the foveolar center the density of the cone cell pedicles ranged from 29,000 to 36,300/mm2, and the density of horizontal cells ranged from 19,000 to 25,100/mm2. Densities of bipolar, Müller, and amacrine cells were determined in only two monkeys and in the baboon. The fact that the cone cell pedicles have a larger diameter than the foveolar cones explains the geometry of the fovea. The morphology of the junction between foveolar cone outer segments and the pigment epithelium reflects the complex metabolism of this functional unit. The comparison with the peripheral primate retina suggests that the densities of horizontal and bipolar cells, but not of amacrine and Müller cells, are correlated with the density of cone cell pedicles.

show abstract

Section: Cones and Pigment Epitheliummentioning

confidence: 73%

“…9; see also Figs. 5 and 6 in Krebs and Krebs, 1987). The density of all of these profiles was equivalent to the density of bipolar cells.…”

Section: Resultsmentioning

confidence: 99%

Section: The Neurons Of the Inner Retinamentioning

confidence: 99%

See 1 more Smart Citation

Quantitative morphology of the central fovea in the primate retina

Krebs

1989

Am. J. Anat.

Self Cite

View full text Add to dashboard Cite

show abstract

“…For example, the amacrine cell density in the visual streak was about 2 times of that in the dorsal retina (Table 1). Furthermore, the densities of the Müller cell were quite different among regions in the retina of the horse, which differed from the relative similarity in the retina of the monkey [3,4].…”

mentioning

confidence: 73%

“…Krebs and Krebs [3,4] concluded that the number of amacrine cells was not related to that of cone cells judging from the similarity of the amacrine cell densities between the fovea and the peripheral retina of the monkey. However, we found a large difference in the amacrine cell densities between visual streak and peripheral retina of the horse.…”

mentioning

confidence: 99%

Quantitative Analysis of the Organization of the Inner Nuclear Layer of the Horse Retina.

Guo

Sugita

2002

The Journal of Veterinary Medical Science

View full text Add to dashboard Cite

ABSTRACT. Four cell types including the bipolar, amacrine, horizontal and Muller cells were investigated quantitatively in the inner nuclear layer of the retina in the horse. Cells were identified on the basis of the morphology and distribution of processes leaving from their somata, cytological features and positional features. The average percentages of the above 4 cell types were 44%, 24%, 1% and 29%, respectively. The average total cell densities in the inner nuclear layer in the visual streak, the nasal and temporal regions, the dorsal and ventral regions of the retina were also estimated. It is expected that the results of this study will supply the basic data for further study of the neural circuits in the horse retina. KEY WORDS: cell type, equine, inner nuclear layer.J. Vet. Med. Sci. 64(9): 847-849, 2002 The inner nuclear layer of the retina contains 4 cell types: the bipolar, amacrine, horizontal and Müller cells. To understand the functions of the cells and neural circuits of the retina completely, the cellular composition in the inner nuclear layer must be known. In the present study, we identified each cell in the inner nuclear layer of the horse retina using a method of serial reconstruction [5]. The percentage and density of each cell type were calculated. On the other hand, in a previous study on the retinal ganglion cells of the horse, we divided the retina into 5 regions according to ganglion cell densities and retinal locations as follows: visual streak, and nasal, temporal, dorsal and ventral regions [1]. The other purpose of the study was to compare cell distributions in the inner nuclear layer among 5 regions.Three eyeballs (L1, L2, R3) from different adult horses (Thoroughbred) were used in the present study. After the horse was killed in a local slaughterhouse, the eyeballs were enucleated quickly and orientations of eyeballs were marked with a marking pen. Eyeballs were hemisected and the retinal blocks with a width of 1 mm and a length of 2-3 mm were sampled from 5 regions of the retina, respectively. The blocks were immersed in 2.5% phosphate buffered glutaraldehyde and 1% paraformaldehyde for 3-4 hr at 4°C, postfixed in 1% osmium tetroxide for 2 hr, dehydrated and embedded in Epok 812. From every retinal block, 16-20 consecutive thin vertical sections were cut at 1 µm with an ultramicrotome (ULTRACUT N, Reichert-Jung Optische Werke AG, Vienna, Austria), mounted onto uncoated glass slides and stained with 0.3% toluidine blue. All consecutive sections were observed under a light microscope and micrographs were taken at 950× using a 100 × oil immersion objective.Cells in the inner nuclear layer of the retina were identified on the basis of the morphology and distribution of processes leaving from their somata [5], cytological features (dark or pale matrix etc.) and positional features (at the outer or inner border of the inner nuclear layer). The bipolar cell injected dendrites from the scleral side of the cell body (Fig. 1B) toward the outer plexiform layer, and extended an axon fr...

show abstract

Ultrastructural Evidence for Lymphatic Capillaries in the Primate Choroid

Krebs¹

1988

Arch Ophthalmol

View full text Add to dashboard Cite

Quantitative morphology of the primate peripheral retina (Macaca irus)

Cited by 23 publications

References 17 publications

Quantitative morphology of the central fovea in the primate retina

Quantitative morphology of the central fovea in the primate retina

Quantitative Analysis of the Organization of the Inner Nuclear Layer of the Horse Retina.

Ultrastructural Evidence for Lymphatic Capillaries in the Primate Choroid

Contact Info

Product

Resources

About