Quantitative model for predicting the electroosmotic flow in dual‐pole nanochannels

Abstract

Developing and assessing nanofluidic systems is time‐consuming and costly owing to the method's novelty; hence, modeling is essential to determine the optimal areas for implementation and to grasp its workings. In this work, we examined the influence of dual‐pole surface and nanopore configuration on ion transfer simultaneously. To achieve this, the two trumpet and cigarette configuration were coated with a dual‐pole soft surface so that the negative charge could be positioned in the nanopore's small aperture. Subsequently, the Poisson–Nernst–Planck and Navier–Stokes equations were simultaneously solved under steady‐state circumstances using varied values physicochemical properties for the soft surface and electrolyte. The pore's selectivity was STrumpet>SCigarette${S}_{{\rm{Trumpet}}} &gt; {S}_{{\rm{Cigarette}}}$, and the rectification factor, on the other hand, was RfCigarette<RfTrumpet${R}_{{f}_{{\rm{Cigarette}}}} &lt; {R}_{{f}_{{\rm{Trumpet}}}}$, when the overall concentration was very low. When the ion partitioning effect is taken into account, we clearly show that the rectifying variables for the cigarette configuration and the trumpet configuration can reach values of 45 and 49.2, when the charge density and mass concentration were 100 mol/m3 and 1 mM, respectively. By using dual‐pole surfaces, the controllability of nanopores’ rectifying behavior may be modified to produce superior separation performance.

Engineering Metal-Organic-Framework (MOF)-Based Membranes for Gas and Liquid Separation

“…Moreover, the enantio-resolutions of phenylephrine, phenylsuccinic acid, chloroquine, and zopiclone were also greater than 2.0. In addition to being used as membranes for chiral separation, MOF can also be used in capillary electrochromatography (CEC) for chiral drug separation based on electroosmotic flow [168]. Ding et al [169] prepared a pepsin-ZIF-8 poly-(GMA-co-EDMA) (poly-(GMA-co-EDMA = poly(glycidyl methacrylate)-co-(ethylene dimethacrylate))column by mixing ZIF-8 into poly-(GMA-co-EDMA) monoliths in CEC and then covalently attaching the chiral selector (i.e., pepsin) to the surface of the amino-modified ZIF-8 by the Schiff base method.…”

Functionalities of electrochemical fluoroquinolone sensors and biosensors

“…Numerous nanomaterials (NMs) and their composites such as gold nanoparticles (Au NPs), carbon nanotubes (CNTs), graphene (Gr) (Akhavan et al 2014 ), and graphene–metal/metal oxide nanocomposites (Sethuraman et al 2016 ) have been employed as perfect biosensor transducers, which offers great improvement in sensitivity by increasing electrochemical signal production and decreasing background noise (Shan et al 2020 ). However, one of the most important factors for achieving an effective process during drug substrate detection is the electroosmotic flow through the nanopores/nanochannels within the NMs used for biosensor modification (Khosravikia 2023 ). In principle, the ion flow through the pore is changed when the analyte enters the pore under the applied potential, and this change is reflected over time in the current recording (Zhang et al 2023 ).…”

Electrokinetic transport phenomena in nanofluidics and their applications

“…However, as nanochannels find more applications in diverse areas, the modification of the channel walls is essential. Therefore, understanding the EOFs in nanochannels with rough and heterogeneous surfaces is highly needed [48]. Lu et al [43] simulated the EOF in rough nanochannels.…”