Quantitative microbiological determination of penicillin††Abstract of a thesis presented by. Robert W. Sager to the Graduate School of the University of Washington in partial fulfillment of the requirements for the degree of Doctor of Philosophy.

Displacement Reactions at Bridgeheads of Bridged Polycarbocyclic Systems.

“…The major part of the products were explained by a mechanism involving free triptycyl radicals. The rates of this reaction and of the diapocamphoyl peroxide decomposition in benzene (69) were such as to indicate very little difference in ease of formation of the bridgehead radicals and the methyl radical (from diacetyl peroxide), but the extra stabilization ordinarily present in tertiary radicals as compared with methyl seemed to be absent. The isolation of triptycene and biphenyl indicated that the triptycyl radical was more reactive Ditriptoyl peroxide 1-Triptycyl triptoate than the phenyl radical.…”

“…Sager (69) that the products could be formed by bimolecular collisions of carboxylate radicals, Bartlett and Lewis (9) pointed out that there were no analogies for a frontside displacement by carbon tetrachloride to give Via as observed. The reaction may be regarded as the most convincing case on record for the occurrence of a true hydrocarbon free radical in the decomposition of an acyl peroxide.…”