Quantitative Messung der Blutströmung mit einem 128-kanaligen Doppler-Gerät - Derzeitiger Forschungsstand und Zukunftsaussichten

We observed instantaneous blood flow velocity profiles at the right and left ventricular outflow tracts, the ascending aorta, and the lower thoracic aorta in human subjects using a newly devised method of real-time multichannel Doppler echocardiography. In 20 apparently healthy subjects, the blood flow velocity profile was successfully obtained in all cases at the right and left ventricular outflow tracts--in 13 cases at the ascending aorta, in 12 cases at the aortic arch, and in ten cases at the lower thoracic aorta. The configuration of the profile was almost flat during systole at the left ventricular outflow tract, the ascending aorta, and the descending aorta. The profile was triangular at the right ventricular outflow tract, where the velocity was faster at the ventricular septal side than at the free wall side, and it was also triangular at the aortic arch, where the velocity was faster at the inner side of the arch than at the outer side. These observations were very similar to those reported by others in previous experimental studies. Thus, the present study demonstrates that it is possible to record noninvasively the instantaneous blood flow velocity profile in humans using this new Doppler echocardiographic instrument.

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The use of angiodynography to quantify blood flow in the canine aorta

Keagy¹,

Palmer²,

Crouch³

et al. 1987

Journal of Vascular Surgery

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Previous attempts to quantify blood flow by means of ultrasound have been hampered by inaccurate diameter measurements and failure to account for the parabolic nature of the cross-sectional velocity profile. Angiodynography (ADG) provides a B-mode image of vessel walls, and the outer flow envelope is constantly monitored to provide phasic diameter measurements throughout the cardiac cycle. Frequency shifts are color-coded to provide a real-time visual display of varying velocity patterns across the vessel lumen throughout the cardiac cycle as well as calculation of average flow velocity and mean blood flow. Simultaneous flow values obtained with ADG were compared with electromagnetic flow probe (EMF) measurements in 12 open-chest dogs. Flow was varied with volume administration and exsanguination, and 201 data points were obtained. The average flow determined by EMF was 2.0 +/- 0.9 L/min compared with 2.04 +/- 0.71 L/min for ADG. The correlation coefficient was 0.88, the y-intercept was close to zero, and the slope approached unity, confirming the ability of ADG to accurately determine volume blood flow rather than merely to establish a flow trend. It is concluded that ADG offers an accurate way of quantifying volume blood flow.

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Quantitative Messung der Blutströmung mit einem 128-kanaligen Doppler-Gerät - Derzeitiger Forschungsstand und Zukunftsaussichten

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Real-time observation of intra- and extracardiac blood flow profile in man using instantaneous B-mode and multichannel Doppler echocardiography

The use of angiodynography to quantify blood flow in the canine aorta

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