Quantitative imaging of fluorine in human teeth by cryogenic laser ionization time-of-flight mass spectrometry

Abstract

The scarcity of technology to visualize the fluorine (F) distribution hinders the comprehensive understanding of the role of anti-caries fluorides. In this study, the liquid nitrogen cooling device was introduced...

Atomic spectrometry update: review of advances in atomic spectrometry and related techniques

“…By observing the spectra in an ICP discharge it was possible to overcome Doppler broadening and resolve the separate lines. Lines of the even Xe isotopes (136,134,132,130,128) were fully resolved for the transitions near 820.860 nm and 841.150 nm. Weak lines of peaks of 124 Xe and 126 Xe with low natural abundances were not observed.…”

“…Typical reproducibility of d 130 Te/ 125 Te was found to be ± 0.07& (2SD) with samples containing 20 ng mL −1 . If d 130 Te is measured at this level of analytical precision, it was concluded that terrestrial samples were unlikely to have a signicant impact from mass-independent Te isotope effects in meteorites and terrestrial samples. Sn isotopes have not been extensively investigated but She et al 165 analysed cassiterite (SnO 2 ) using LA-MC-ICP-MS.…”

“…This improved the analytical performance of fs-LIMS for the analysis of non-conductive samples. Furthermore, a novel LIMS method for high spatially resolved mapping of F was developed by Ma et al , 130 who employed a cryogenic laser ionisation source to eliminate the interference of water-derived species at m / z 19. The Cryo-LI-TOFMS was validated mapping the distribution of F concentration in human teeth, with a spatial resolution of 20 μm.…”

Atomic spectrometry update: review of advances in the analysis of clinical and biological materials, foods and beverages

“…The determination of fluorine is a challenge with conventional atomic spectrometric techniques, so Ma et al 185 reported an approach employing cryogenic laser ionisation TOF-MS to assess the F content of teeth . The setup used liquid nitrogen to cool the ion source to −25 °C and pressurised the chamber to 300 Pa with He gas.…”