Quantitative imaging and semiotic phenotyping of mitochondrial network morphology in live human cells
Sophie Charrasse,
Victor Racine,
Charlotte Saint-Omer
et al.
Abstract:The importance of mitochondria in tissue homeostasis, stress responses and human diseases, combined to their ability to transition between various structural and functional states, makes them excellent organelles for monitoring cell health. There is therefore a need for technologies to accurately analyze and quantify changes in mitochondrial organization in a variety of cells and cellular contexts. Here we present an innovative computerized method that enables accurate, multiscale, fast and cost-effective anal… Show more
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