Quantitative Fourier transform infrared/attenuated total reflectance analysis of ketoprofen in some pharmaceutical formulations

Quantitative analysis of automotive exhaust gas by Fourier Transform Infrared spectroscopy

“…The minimisation is done by finding the values of the coefficients that satisfy the first derivate equations equal to zero, and the concentrations of the different components found in the sample spectrum are calculated (Van Overbeke et al, 1995). To improve the analysis accuracy, the concentrations of the different gases were divided into several subsets.…”

Quantification and Classification of Diclofenac Sodium Content in Dispersed Commercially Available Tablets by Attenuated Total Reflection Infrared Spectroscopy and Multivariate Data Analysis

“…Van Overbeke et al used ATR FT-IR to quantify ketoprofen in pharmaceutical formulations such as capsules and injection ampoules, in combination with partial least-squares (PLS) analysis [ 35 ]. Similarly, Boyer et al proposed an analytical method without prior sample treatment for the determination of niflumic acid in a pharmaceutical gel by ATR FT-IR and PLS calibration with a root mean square error of prediction (RMSEP) equal to 0.2 for the validation set [ 36 ].…”

Direct determination of niflumic acid in a pharmaceutical gel by ATR/FTIR spectroscopy and PLS calibration

“…The attenuated total reflectance/Fourier transform infrared spectroscopy (ATR/FTIR), originally developed by Fahrenfort [9], was suggested as a sensible technique to analyse pharmaceutical formulations such as solids, semi-solids and liquids [10,11]. However, very limited applications have been reported for quantification of drugs [12][13][14][15][16] although ATR is a method, which simplifies sample handling, avoids the use of organic solvents and thus saves time and chemical reagents. The main drawback of spectral data is the overlapped information contained in the signal for chemical mixtures.…”