The composite strata of coal floor is an important barrier to block the lifting and bursting of thick limestone groundwater into the mining space. Taking J3 and J4 mining areas of Handicapping Coalfield as the object, this paper selected the thickness ratio of plastic brittle rock core recovery rate, composite comprehensive strength, Equivalent water barrier coefficient, Effective water-resistant layer thickness and fault complexity as the main control factors, and determined the comprehensive weight of index factors based on the entropy weight theory. Using the Archaist vulnerability index grading evaluation model, the water-isolation ability of the composite strata in the floor of J 16-17 coal seam is quantitatively evaluated and divided into five grades: extremely weak, weak, medium, strong and extremely strong. The results show that the areas with strong and extremely strong water-isolation ability of the composite strata of coal floor account for 38.67% of the total area, the areas with moderate and extremely weak water-isolation ability account for 51.45%, and the areas with weak and extremely weak water-isolation ability account for 9.88%. In this paper, the coupling effect of multiple factors on composite strata is considered, and the quantitative classification and zoning discrimination of water-isolation ability of composite strata is realized, which provides technical support for accurate evaluation of water-inrush risk of coal floor.