Quantitative estimation of increased vascular permeability in acute inflammatory reaction in the chicken skin

Pillai, A. G. R.; Awadhiya, R.P.; Vegad, J. L.

doi:10.1007/bf00362795

Cited by 8 publications

(4 citation statements)

References 12 publications

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“…For this, the animal is passively sensitised by an intradermal injection of antibody, and after a suitable interval, termed the latent period, it is challenged by an intravenous injection of antigen. In the chicken, studies on PCA revealed an intense 'blueing' indicative of an increase in vascular permeability (Chand et al, 1976;Burns and Maxwell, 1981;Pillai et al, 1987a); and also marked emigration of heterophils, monocytes and basophils (Chand et al, 1976). The chicken mesentery is particularly rich in mast cells.…”

Section: Introductionmentioning

confidence: 99%

Pathology of passive mesenteric anaphylaxis in the chicken

Pillai¹,

Awadhiya²,

Vegad³

1988

Avian Pathology

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Section: Introductionmentioning

confidence: 99%

Pathology of passive mesenteric anaphylaxis in the chicken

Pillai¹,

Awadhiya²,

Vegad³

1988

Avian Pathology

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“…This was based on the size of the blue area and the intensity of its colour on both the upper and the undersurface of the lesion (Pillai et al, 1988b). The values were scored on an arbitrary scale ofO, ±, +, ++, + + + and + + + +.…”

Section: Dye Techniquementioning

confidence: 99%

“…The increased vascular permeability in the cutaneous lesion was also estimated quantitatively by the method described by Pillai et al (1988b) and Katiyar et al (1992) for the chicken skin.…”

Section: Dye Techniquementioning

confidence: 99%

Pathology of inflammatory‐reparative response in punched wounds of the chicken skin

Katiyar¹,

Vegad²,

Awadhiya³

1992

Avian Pathology

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SUMMARYVascular and cellular responses were examined sequentially in punched wounds of the chicken skin. The 'dye' and the 'colloidal carbon' technique revealed that the increased permeability response was immediate and sustained. The response attained its peak at 1 hour and persisted for up to 6 hours, but the increased permeability was prolonged over a period of 48 h. The increase in vascular permeability at all stages was confined to venules and small veins only. In the later stages of healing, the newly formed vessels in the granulation tissue were leaky.The initial migration of leukocytes comprised heterophils and monocytoid cells. This was soon followed by infiltration of some basophils. A striking feature of the reaction, in the granulation tissue, was that the monocytoid cells apparently coalesced, formed syncytia, and even what appeared to be distinct multinucleated giant cells. Whereas mast cells participated in the early stages, they were absent in the granulation tissue. Proliferation of the fibroblasts began around 18 h, angiogenesis and re-epithelialization at 3 days, and the healing was complete by about 7 days.

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“…Evans blue exuded in the cutaneous lesions was determined quantitatively, using the technique described by Pillai et al (1988) and Katiyar et al (1992a) for the chicken skin. Briefly, each lesion was excised with sufficient surrounding tissue, weighed, chopped into fine fragments and placed in 3 ml formamide for 48 h at 37°C for extraction of the dye.…”

mentioning

confidence: 99%