Quantitative elemental bioimaging: an antibody-based double-labelling method to quantify the cell-specific distribution of silver nanoparticles in lung tissue sections

Abstract

Silver nanoparticles (Ag-NP) are contained in many consumer products although their uptake especially by respiration bears potential risks for human health. Quantitative data about the systemic distribution of Ag-NP at...

Atomic spectrometry update: review of advances in atomic spectrometry and related techniques

“…Elemental tagging to facilitate cellular imaging is another example of tagging at the cellular level. Reifschneider et al 17 used a double labelling strategy to quantitatively determine Ag NPs in lung tissue. Lung tissue samples were incubated with an anti-rat CD68 antibody.…”