Quantitative EEG effects of carbamazepine, oxcarbazepine, valproate, lamotrigine, and possible clinical relevance of the findings

Clemens, Béla; Ménes, Andrea; Piros, Pálma; Bessenyei, Mónika; Altmann, Anna; Jerney, Judit; Kollár, Katalin; Rosdy, Beáta; Rózsavölgyi, Margit; Steinecker, Katalin; Hollódy, Katalin

doi:10.1016/j.eplepsyres.2006.05.003

Cited by 74 publications

(45 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This effect is due to medication, particularly carbamazepine. This drug is known to increase theta power (Clemens et al, 2006), as confirmed in this study. Both spectral findings and LORETA showed that drug-related increase was present across the entire theta range in all voxels.…”

Section: Patients Under Medication (Group2)supporting

confidence: 86%

Theta EEG source localization using LORETA in partial epilepsy patients with and without medication

Clemens

Bessenyei

Fekete

et al. 2010

Clinical Neurophysiology

View full text Add to dashboard Cite

Objective. To investigate and localize the sources of spontaneous, scalp-recorded theta activity in patients with partial epilepsy (PE).Methods. 9 patients with beginning, untreated PE (Group1), 31 patients with already treated PE (Group2), and 14 healthy persons were investigated by means of spectral analysis and LORETA, low resolution electromagnetic tomography (1 Hz very narrow band analysis, age-adjusted, Z-scored values). The frequency of main interest was 4 to 8 Hz Results. Group analysis. Group1 displayed bilateral theta maxima in the temporal theta area (TTA), parietal theta area (PTA), and frontal theta area (FTA). In Group2, theta activity increased all over the scalp as compared to the normative mean (Z=0) and also to Group1. Maximum activity was found in the TTA, PTA, and FTA. However, in the PTA and FTA the centers of the abnormality shifted towards the medial cortex. Individual analysis: all the patients showed preferential activation (maximum Zvalues) within one of the three theta areas. 2Conclusion. EEG activity in the theta band is increased in anatomically meaningful patterns in PE patients, which differs from the anatomical distribution of theta in healthy persons.Significance. The findings contribute to our understanding of the sources of theta rhythms and the pathophysiology of PE.

show abstract

Section: Patients Under Medication (Group2)supporting

confidence: 86%

Theta EEG source localization using LORETA in partial epilepsy patients with and without medication

Clemens

Bessenyei

Fekete

et al. 2010

Clinical Neurophysiology

View full text Add to dashboard Cite

show abstract

“…Com intoxicação acentuada, a frequência de ondas diminui mais e sua amplitude aumenta 11 . Ácido valpróico, lamotrigina, tiagabina e vigabatrina não alteram 12 ou alteram discretamente a atividade no EEG 13 .…”

Section: Identificaçãounclassified

“…Ritmo delta não aparece nos EEGs de adultos normais em vigília, mas artefatos oculares em eletrodos anteriores são frequentes e podem gerar confusão 14 . Por outro lado ritmo delta é comum nos EEGs de crianças pequenas e podem não representar anormalidade, assim como em alguns idosos, nos quais ondas delta, nas regiões temporais, podem ser indicativas de patologia vascular, mas não necessariamente doença estrutural 13 . No sono, estuda-se a atividade de fundo em busca de assimetrias e paroxismos.…”

Section: Corpo Do Laudounclassified

Practical suggestions for writing routine EEG reports

Kanda¹,

Cury²,

Lovatel³

et al. 2014

RNC

View full text Add to dashboard Cite

RESUMOUma queixa comum feita pelos médicos solicitantes é que o laudo do Eletrencefalograma (EEG) faz pouco sentido e não contribui para o diagnóstico. Assim, os autores, baseados em seu cotidiano e na literatura, fazem breves comentários e sugestões a respeito da elaboração do laudo do EEG abrindo o tema para discussão. Uma abordagem sistemática da descrição (laudo) é necessária para que os achados contribuam positivamente no processo propedêutico. Assim a descrição do EEG deve ser dividida em algumas partes: 1.identificação do laboratório e paciente; 2.características técnicas do equipamento e condições do exame; 3. corpo do laudo, que trata da descrição dos achados eletrográficos; 4.conclusão, onde é referido se o exame é normal ou não e finalmente; 5.correlação eletroclínica, quesito final e de interesse do clínico solicitante, e o momento no qual se tenta confirmar ou não as hipóteses diagnósticas. Advoga-se neste artigo que o laudo deve ser claro e objetivar o diagnóstico eletroclínico, pois, o EEG é ferramenta de auxílio diagnóstico tanto para o neurologista quanto para o clínico e o pediatra. Unitermos. Eletroencefalografia, EEG, Diagnóstico, MétodosCitação. Kanda RG, Cury IJ, Lovatel ATB, Kanda PAM. Sugestões práticas para a descrição do EEG de rotina. ABSTRACTA common complaint made by some referring physicians about the electroencephalogram (EEG) report is that it makes little sense and often does not help in the diagnosis or management of their patients. Thus, opening the topic for discussion, the authors, make brief comments and suggestions regarding the report of the EEG. A systematic approach to the description is required so that the findings contribute positively in the report process. Consequently, the description of the EEG should be divided into several parts: 1. laboratory and patient identification; 2. equipment technical characteristics and test conditions; 3. description of electroencephalographic findings; 4.Conclusion, which state that the examination is normal or not; 5. electroclinical correlations that is what matters to the requesting clinician, and it is the moment one attempts to confirm the clinical diagnostic hypothesis. This article advocates that the EEG report should be clear and seek electroclinical diagnosis because the EEG is a diagnostic tool for neurologists, clinicians, and pediatricians.

show abstract

“…The alpha rhythm is also prone to frequency changes in some disorders as epilepsy, dementia and some tumours, and in treatment with antiepileptic drugs [27][28][29][30][31][32][33][34][35] to some extent implemented to find alpha rhythm frequencies in short segments (a few seconds), but fully automatic analysis is not commonly applied clinically.…”

Section: Discussionmentioning

confidence: 99%

“…Peak-to-peak intervals outside the alpha band (20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36) Hz (period time: 0.0781s -0.1406s)) and peaks with amplitude difference below 10 ȝV in two consecutive half waves were discarded.…”

Section: Automatic Assessment Of Alpha Waves In Time Domain (Atd)mentioning

confidence: 99%

A New Method for Quantification and Assessment of Epileptiform Activity in EEG with Special Reference to Focal Nocturnal Epileptiform Activity

Larsson¹,

Wilson²,

Eeg‐Olofsson

2008

Brain Topogr

View full text Add to dashboard Cite

Quantitative EEG effects of carbamazepine, oxcarbazepine, valproate, lamotrigine, and possible clinical relevance of the findings

Cited by 74 publications

References 26 publications

Theta EEG source localization using LORETA in partial epilepsy patients with and without medication

Theta EEG source localization using LORETA in partial epilepsy patients with and without medication

Practical suggestions for writing routine EEG reports

A New Method for Quantification and Assessment of Epileptiform Activity in EEG with Special Reference to Focal Nocturnal Epileptiform Activity

Contact Info

Product

Resources

About