Quantitative Determination of Arbutin in Malus sylvestris Leaves by High-Performance Liquid Chromatography

Nesterova, N. V.; Самылина, И. А.; Kuzmenko, A. N.; Kuzmenko, I. A.; Krasnyuk, I. I.; Evgrafov, A. A.

doi:10.3103/s0027131419010097

Cited by 6 publications

(1 citation statement)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Plants from at least seven genera within the Proteaceae, e.g., Bellendena [25], Cenarrhenes [25], Grevillea [59], Hakea [60], Heliciopsis [63], Leucadendron [73] and Persoonia [25] biosynthesize arbutin. The family Rosaceae includes the highest number of genera that produce the compound, including Cotoneaster [50], Eriobotrya [53], Fragaria [57], Malus [77], Prunophora [67], Pyrus [103], Rosa [126] and Sorbaria [140] (Table 1).…”

Section: Distribution Of Arbutin (1) In the Plant Kingdommentioning

confidence: 99%

Arbutin: Occurrence in Plants, and Its Potential as an Anticancer Agent

Nahar

Al-Groshi

Kumar³

et al. 2022

Molecules

View full text Add to dashboard Cite

Arbutin, a hydroquinone glucoside, has been detected in ca. 50 plant families, especially in the plants of the Asteraceae, Ericaceae, Proteaceae and Rosaceae families. It is one of the most widely used natural skin-whitening agents. In addition to its skin whitening property, arbutin possesses other therapeutically relevant biological properties, e.g., antioxidant, antimicrobial and anti-inflammatory, as well as anticancer potential. This review presents, for the first time, a comprehensive overview of the distribution of arbutin in the plant kingdom and critically appraises its therapeutic potential as an anticancer agent based on the literature published until the end of August 2022, accessed via several databases, e.g., Web of Science, Science Direct, Dictionary of Natural Products, PubMed and Google Scholar. The keywords used in the search were arbutin, cancer, anticancer, distribution and hydroquinone. Published outputs suggest that arbutin has potential anticancer properties against bladder, bone, brain, breast, cervix, colon, liver, prostate and skin cancers and a low level of acute or chronic toxicity.

show abstract

Section: Distribution Of Arbutin (1) In the Plant Kingdommentioning

confidence: 99%

Arbutin: Occurrence in Plants, and Its Potential as an Anticancer Agent

Nahar

Al-Groshi

Kumar³

et al. 2022

Molecules

View full text Add to dashboard Cite

show abstract

Evaluation of Some Quality Indicators and Prospects for Using Different Varieties of Pear Fruit in Medicine

Dosayeva

Nesterova

2021

Mediko-farmacevtičeskij žurnal "Pulʹs"

View full text Add to dashboard Cite

In this article, the authors studied the macrodiagnostic characteristics of pear fruits of three varieties that are most common in the food markets of the Russian Federation. To date, the standardization of such promising and rich in the composition of biologically active substances (BAS) raw materials is carried out only in accordance with the state Standards of the food industry. The research was aimed at developing quality indicators necessary for identifying raw materials that could be considered as a source for obtaining medicinal substances. For all the studied fruits, the total content of extractive substances, organic acids in terms of malic acid and pectin substances was determined. The content of extractive substances was from 15.8% to 17.6%, organic acids - from 0.34% to 1.09%, pectin substances - from 1.15% to 1.87%. As a result of the qualitative reactions, the data of TLC-spectrophotometric method pear fruits, the varieties which are most widely cultivated on the territory of the Russian Federation, was identified as arbutin, which allows to consider the material as a promising source of valuable biologically-active substances and actualizes the further research aimed at developing modern methods of standardization for inclusion in the proposed regulatory documentation.

show abstract

Study of Morphometric Characteristics of Alder Leaves of Pharmacopoeial Species

Nesterov

Литвинова

Vasalatiy

2021

Mediko-farmacevtičeskij žurnal "Pulʹs"

View full text Add to dashboard Cite

To expand the raw material base of medicinal plant raw materials, a promising area of research is the study of additional types of raw materials that can be harvested from already used medicinal and food plants. Given the complexity of harvesting alder seeds, researchers are interested in the leaves of this plant, a wide range of biologically active substances that cause anti-inflammatory, astringent and antioxidant effects. The first stage of standardization of raw materials is the definition of morphologically significant features, based on the generalization of which the section "External features" is developed. The analysis of morphological features of freshly harvested, dried and frozen leaves of gray alder (Alnus incana Moench) and black alder (A. glutinosa Gaerth) harvested from wild plants in mixed forests of the Moscow region revealed diagnostically significant features and found that the method of conservation does not affect the occurrence of the identified features. Since it is planned to use both types of alder for the preparation of a new type of raw material "Alder leaves", a generalized formulation is proposed for raw materials that are a mixture of species.

show abstract

Quantitative Determination of Arbutin in Malus sylvestris Leaves by High-Performance Liquid Chromatography

Cited by 6 publications

References 3 publications

Arbutin: Occurrence in Plants, and Its Potential as an Anticancer Agent

Arbutin: Occurrence in Plants, and Its Potential as an Anticancer Agent

Evaluation of Some Quality Indicators and Prospects for Using Different Varieties of Pear Fruit in Medicine

Study of Morphometric Characteristics of Alder Leaves of Pharmacopoeial Species

Contact Info

Product

Resources

About