Quantitative computer-assisted analysis of left ventricular wall thickening and motion by 2-dimensional echocardiography in acute myocardial infarction

Henschke, Claudia I.; Risser, Thomas A.; Sándor, Tamás; Hanlon, William B.; Neumann, Alexander; Wynne, Joshua

doi:10.1016/0002-9149(83)90512-x

Cited by 36 publications

(3 citation statements)

References 15 publications

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“…The changes seen in our canine model coincide with those observed in patients with transmural and nontransmural infarctions [17]. Henschke et al [17} observed that most patients with nontransmural infarctions exhibited decreased wall thickening without wall thinning, and that the wall thickening returned to normal within 2 weeks after infarction.…”

Section: Discussionsupporting

confidence: 85%

Quantitative analysis of left ventricular function: pre- and postischemic two-dimensional echocardiography in dogs

Henschke¹,

Ellis²,

Risser³

et al. 1984

American Journal of Roentgenology

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We present findings from quantitative analysis of thickening and contraction for every 2#{176} of arc of the ventricular circumference, thus allowing better assessment and follow-up of subtle abnormalities.To assess the usefulness of the technique, dogs were studied before and after experimental occlusion of the left descending coronary artery. Materials and MethodsAnimals used in this study were maintained in accordance with the guidelines of the Animal Preparation and InstrumentationDownloaded from www.ajronline.org by 54.191.190.102 on 05/11/18 from IP address 54.191.190.102.

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Section: Discussionsupporting

confidence: 85%

Quantitative analysis of left ventricular function: pre- and postischemic two-dimensional echocardiography in dogs

Henschke¹,

Ellis²,

Risser³

et al. 1984

American Journal of Roentgenology

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“…Quantitative analysis of WM and WT using centerline methods provides better diagnostic accuracy but is more time-consuming (1,27). In clinical practice, regional ventricular function is therefore usually assessed qualitatively or semiquantitatively by visual inspection of MRI cine loops (13,14).…”

Section: Discussionmentioning

confidence: 99%

Qualitative and quantitative analysis of regional left ventricular wall dynamics using real‐time magnetic resonance imaging: Comparison with conventional breath‐hold gradient echo acquisition in volunteers and patients

Plein

Smith

Ridgway

et al. 2001

Magnetic Resonance Imaging

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Index terms: magnetic resonance imaging; real-time imaging; left ventricle; regional function; wall motion; wall thickening ABNORMALITIES OF REGIONAL left ventricular wall dynamics at rest or during stress are sensitive markers of myocardial ischemia (1,2). Cardiac magnetic resonance imaging (MRI) provides accurate and reproducible measurements of regional left ventricular wall motion (WM) and wall thickening (WT) for both qualitative and quantitative analysis (3-12). MRI is a noninvasive imaging modality that offers excellent spatial resolution and tissue contrast and, unlike echocardiography and x-ray angiography, provides excellent depiction of both endocardial and epicardial contours. This may lead to higher diagnostic accuracy of stress MRI for detection of inducible WM abnormalities, compared with stress echocardiography (13,14). However, until recently MRI has had the disadvantage of relatively slow image acquisition. With conventional techniques, a 10 -20-second acquisition time is required per slice and up to 15 minutes for a complete data set of the left ventricle (LV) (15). Furthermore, signals in conventional MRI acquisition are time averaged, and each slice has to be acquired over several heartbeats in one breath hold. This is unsuitable in imaging of patients with cardiac arrhythmias and in patients who cannot breath hold. Faster image acquisition is therefore crucial in establishing cardiac MRI as a useful and cost-effective clinical tool. This is particularly important in stress MRI studies in order to shorten the exposure of patients to pharmacological stress agents and to allow early detection of WM abnormalities.With high-performance gradient systems and recently developed ultrafast hybrid MRI acquisition sequences, significant reductions in image acquisition times can be achieved in cardiac . With these sequences, multiphase cine images of the heart can be acquired in real time in a single RR interval, i.e., without time averaging. Measurements of ventricular dimensions and global ventricular function from realtime-acquired MRI data sets have shown good correlation with conventional fast gradient echo acquisition (22)(23)(24). Visual assessment of regional function from real-time MRI has been shown to be feasible (25). However, to date no comparison has been made between real-time and conventional MRI acquisition for qualitative and quantitative assessment of WM and WT. It is uncertain how the lower spatial resolution and signalto-noise ratio (SNR) of real-time-acquired images will affect the accuracy and reproducibility of such measurements.

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“…In one of these studies (9) wall thickness abnormalities approached the actual loss of contractility more closely than wall motion abnormalities. Furthermore, several studies have demonstrated that wall motion abnormalities overestimate ischemic areas and are less accurate than wall thickening to distinguish ischemic from nonischemic myocardium (31, 36,37). Therefore, wall thickening rather than wall motion is more likely to represent the actual regional left ventricular function in patients with completed infarction.…”

Section: Previous Findingsmentioning

confidence: 99%

Quantitative analysis of regional left ventricular function after myocardial infarction in the pig assessed with cine magnetic resonance imaging

Holman

Vliegen

Geest

et al. 1995

Magnetic Resonance in Med

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To assess the accuracy of quantitative analysis of global and regional wall motion and wall thickening of the left ventricle with cine magnetic resonance (MR), images obtained in eight pigs before and after myocardial infarction were compared with those obtained using gadolinium diethylenetriaminepentaacetic acid (Gd-DTPA)-enhanced multislice spin-echo MR imaging and determination of pathology. The region with abnormal wall motion and wall thickening, as determined with cine MR imaging, identified the same region of infarction as indicated by Gd-DTPA-enhanced spin-echo MR imaging and pathology. Within the infarcted region wall motion and wall thickening analyzed with the centerline method were significantly reduced. We conclude that the use of quantitative analysis of cine MR images accurately determines localization and extent of regional left ventricular dysfunction in the infarcted heart in vivo. This analysis using dedicated software including the centerline method allows sequential assessment of regional left ventricular function in normal and infarcted hearts.

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Quantitative computer-assisted analysis of left ventricular wall thickening and motion by 2-dimensional echocardiography in acute myocardial infarction

Cited by 36 publications

References 15 publications

Quantitative analysis of left ventricular function: pre- and postischemic two-dimensional echocardiography in dogs

Quantitative analysis of left ventricular function: pre- and postischemic two-dimensional echocardiography in dogs

Qualitative and quantitative analysis of regional left ventricular wall dynamics using real‐time magnetic resonance imaging: Comparison with conventional breath‐hold gradient echo acquisition in volunteers and patients

Quantitative analysis of regional left ventricular function after myocardial infarction in the pig assessed with cine magnetic resonance imaging

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