Quantitative autoradiographic analysis of the distribution of [3H]muscimol binding to GABA receptors in chick brain

Stewart, Michael G.; Bourne, Rachel C.; Chmielowska, Jolanta; Kálmán, Mihály; Csillag, András; Stanford, David R.

doi:10.1016/0006-8993(88)90245-4

Cited by 21 publications

(11 citation statements)

References 17 publications

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“…This is in line with earlier studies that determined receptor levels in the nidopallium of various bird species Stewart et al 1988Stewart et al ,1999Mitsacos et al 1990;Aamodt et al 1992;Veenman et al 1994;Ben-Ari et al 1997;Salvatierra et al 1997). Pigeons showed higher AMPA and NMDA receptor concentrations in the nidopallium when compared to other birds, while the amount of GABA A receptor densities seemed to be similar in pigeons, chicks and zebra finches (Stewart et al 1988;Henley and Barnard 1990;Veenman et al 1994;Martinez de la Torre et al 1998;Stewart et al 1999;Pinaud and Mello 2007). The present study reports for the first time kainate receptor densities in the pigeon's pallium.…”

Section: Subdivisions Of the Nclsupporting

confidence: 94%

“…Kainate receptors seemed to be very low in rat FR2 and Cg1, while they did not differ substantially between human BA10 and the NCL, and between the CDL and the human cingulate cortex (Palomero-Gallagher et al 2009). By contrast, the amounts of GABA A receptors were equally distributed in the prefrontal areas of all the investigated species here and also in the NCL of pigeons and chicks (Stewart et al 1988). The same is true for the CDL and the human as well as the macaque cingulate cortex (Bozkurt et al 2005;Palomero-Gallagher et al 2009).…”

Section: Comparison To Mammals and Functional Considerationsmentioning

confidence: 73%

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The receptor architecture of the pigeons’ nidopallium caudolaterale: an avian analogue to the mammalian prefrontal cortex

et al. 2011

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The avian nidopallium caudolaterale is a multimodal area in the caudal telencephalon that is apparently not homologous to the mammalian prefrontal cortex but serves comparable functions. Here we analyzed binding-site densities of glutamatergic AMPA, NMDA and kainate receptors, GABAergic GABA(A), muscarinic M(1), M(2) and nicotinic (nACh) receptors, noradrenergic α(1) and α(2), serotonergic 5-HT(1A) and dopaminergic D(1)-like receptors using quantitative in vitro receptor autoradiography. We compared the receptor architecture of the pigeons' nidopallial structures, in particular the NCL, with cortical areas Fr2 and Cg1 in rats and prefrontal area BA10 in humans. Our results confirmed that the relative ratios of multiple receptor densities across different nidopallial structures (their "receptor fingerprints") were very similar in shape; however, the absolute binding densities (the "size" of the fingerprints) differed significantly. This finding enables a delineation of the avian NCL from surrounding structures and a further parcellation into a medial and a lateral part as revealed by differences in densities of nACh, M(2), kainate, and 5-HT(1A) receptors. Comparisons of the NCL with the rat and human frontal structures showed differences in the receptor distribution, particularly of the glutamate receptors, but also revealed highly conserved features like the identical densities of GABA(A), M(2), nACh and D(1)-like receptors. Assuming a convergent evolution of avian and mammalian prefrontal areas, our results support the hypothesis that specific neurochemical traits provide the molecular background for higher order processes such as executive functions. The differences in glutamate receptor distributions may reflect species-specific adaptations.

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Section: Subdivisions Of the Nclsupporting

confidence: 94%

Section: Comparison To Mammals and Functional Considerationsmentioning

confidence: 73%

The receptor architecture of the pigeons’ nidopallium caudolaterale: an avian analogue to the mammalian prefrontal cortex

et al. 2011

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“…in that both ligand binding studies and immunohistochemistry indicate a scarcity of GABAA~BDZ and GABAB receptors (Penney and Pan, 1986;Diet1 et al, 1988;Stewart et al, 1988;Chu et al, 1990;Canonaco, 1991Canonaco, ,1992, although portions of the septum are rich in GABAergic fibers and neurons in both mammals and birds (Nagai et al, 1984;Mugnaini and Oertel, 1985;Veenman and Reiner, 1994). In situ hybridization studies, however, indicate the presence of GABAA/BDZ receptor mRNA in neurons of the septum of mammals and birds Churchill et al, 1991;Glencorse et al, 1991;Zhang et al, 1991;Wisden et al, 1992).…”

Section: CL Veenman Et Almentioning

confidence: 97%

“…Among the isthmic nuclei, ours and other ligand binding studies showed that Ipc, which was relatively rich in GABAergic terminals, was only modest in GABAA and GABAB binding sites, but very rich in BDZ binding sites, while Imc was poor in both binding sites and terminals (Dietl et al, 1988;Stewart et al, 1988). Our immunohistochemical data (on labeling directed a t the beta subunit of the GABAA/BDZ receptor, which forms part of the recognition site for BDZ) also showed Ipc to have a neuropil well labeled for GABA*/BDZ and showed Imc to have widely spaced perikarya well labeled for GABAAiBDZ receptors.…”

Section: Diencephalonmentioning

confidence: 98%

Distributions of GABA_A, GABA_B, and benzodiazepine receptors in the forebrain and midbrain of pigeons

Veenman

Albin

Richfield

et al. 1994

J of Comparative Neurology

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Autoradiographic and immunohistochemical methods were used to study the distributions of GABAA, GABAB and benzodiazepine (BDZ) receptors in the pigeon fore- and midbrain. GABAA, GABAB and BDZ binding sites were found to be abundant although heterogeneously distributed in the telencephalon. The primary sensory areas of the pallium of the avian telencephalon (Wulst and dorsal ventricular ridge) tended to be low in all three binding sites, while the surrounding second order belt regions of the pallium were typically high in all three. Finally, the outermost rind of the pallium (termed the pallium externum by us), which surrounds the belt regions and projects to the striatum of the basal ganglia, was intermediate in all three GABAergic receptors types. Although both GABAA and benzodiazepine receptors were abundant within the basal ganglia, GABAA binding sites were densest in the striatum and BDZ binding sites were densest in the pallidum. Among the brainstem regions receiving GABAergic basal ganglia input, the anterior and posterior nuclei of the ansa lenticularis showed very low levels of all three receptors, while the lateral spiriform nucleus and the ventral tegmental area/substantia nigra complex contained moderate abundance of the three binding sites. The dorsalmost part of the dorsal thalamus (containing nonspecific nuclei) was rich in all three binding sites, while the more ventral part of the dorsal thalamus (containing specific sensory nuclei), the ventral thalamus and the hypothalamus were poor in all three binding sites. The pretectum was also generally poor in all three, although some nuclei displayed higher levels of one or more binding sites. The optic tectum, inferior colliculus, and central gray were rich in all three sites, while among the isthmic nuclei, the parvicellular isthmic nucleus was conspicuously rich in BDZ sites. The results show a strong correlation of the regional abundance of GABA binding sites with previously described distributions of GABAergic fibers and terminals in the avian forebrain and midbrain. The regional distribution of these binding sites is also remarkably similar to that in mammals, indicating a conservative evolution of forebrain and midbrain GABA systems among amniotes.

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“…The whole ventral hyperstriatum can be regarded as a group of tertiary areas, and its interpretation as a multimodal integrative area is also based on ethological and anatomical studies [Bradley and Horn, 1981;Bradley et al, 1981;Horn, 1981;McCabe et al. 1982;Stewart et al, 1984Stewart et al, , 1988Bullock et al, 1987;McCabe and Horn, 1988;Patel and Stewart, 1988;Patel et al, 1988;Csillag et al, 1990;Mogenson and Divac, 1990].…”

Section: Birds and Mammalsmentioning

confidence: 99%

Quantitative Development of Brain and Brain Structures in Birds (Galliformes and Passeriformes) Compared to that in Mammals (Insectivores and Primates) (Part 2 of 2)

1991

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The brain weight and brain structure volumes of galliform and passeriform birds were calculated and related to body weight. The total brains and 14 brain regions were investigated in order to calculate factors by which these structures in passeriforms exceed those in galliforms in size. The larger passeriform brains have larger telencephala, especially ventral hyperstriata and neostriata. The enlargement of total brain and telencephalon resembles that in primates, compared to insectivores, within mammals. The enlargement of the ventral hyperstriata + neostriata in passeriforms is fundamentally similar to that of the isocortex in mammals: it reflects an expansion of multimodal integrational capacities, as the ventral hyperstriatum and neostriatum are occupied exclusively or primarily by multimodal integrational areas as is the isocortex.

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Quantitative autoradiographic analysis of the distribution of [3H]muscimol binding to GABA receptors in chick brain

Cited by 21 publications

References 17 publications

The receptor architecture of the pigeons’ nidopallium caudolaterale: an avian analogue to the mammalian prefrontal cortex

The receptor architecture of the pigeons’ nidopallium caudolaterale: an avian analogue to the mammalian prefrontal cortex

Distributions of GABA_A, GABA_B, and benzodiazepine receptors in the forebrain and midbrain of pigeons

Quantitative Development of Brain and Brain Structures in Birds (Galliformes and Passeriformes) Compared to that in Mammals (Insectivores and Primates) (Part 2 of 2)

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Quantitative autoradiographic analysis of the distribution of [3H]muscimol binding to GABA receptors in chick brain

Cited by 21 publications

References 17 publications

The receptor architecture of the pigeons’ nidopallium caudolaterale: an avian analogue to the mammalian prefrontal cortex

The receptor architecture of the pigeons’ nidopallium caudolaterale: an avian analogue to the mammalian prefrontal cortex

Distributions of GABAA, GABAB, and benzodiazepine receptors in the forebrain and midbrain of pigeons

Quantitative Development of Brain and Brain Structures in Birds (Galliformes and Passeriformes) Compared to that in Mammals (Insectivores and Primates) (Part 2 of 2)

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Distributions of GABA_A, GABA_B, and benzodiazepine receptors in the forebrain and midbrain of pigeons