Quantitative assessment of the relationship of slow-wave heart rate oscillations and motor activity in rat fetuses with maternal respiratory and cardiac activity

Timofeeva, O. P.; Vdovichenko, N. D.; Bursian, A. V.

doi:10.1134/s0022093015050075

Cited by 3 publications

(2 citation statements)

References 16 publications

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“…Decelerations are superseded by acceleration reactions that are typical of a mature organism on E19-20. It is related to development of coordinating function of nervous system [22].…”

Section: Development Of Cross-system Interactions In Perinatal Ontogementioning

confidence: 99%

Ontogenetic Development of Neural and Muscular Rhythmic Activity and Its Regulation in Mammals during Perinatal Period

Кузнецов¹,

Vdovichenko²,

Dmitrieva³

et al. 2018

Evolutionary Physiology and Biochemistry - Advances and Perspectives

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This review covers our recent advantages in studying the ontogenetic aspects of physiological mechanisms underlying regulation of rhythmic behavior. We have revealed that excitation patterns that emerged at early stages of phylogenetic development of life forms contribute greatly to the rhythmic activity of living vertebrates and invertebrates. These patterns govern spontaneous excitation, which is easily observed during the early stage of ontogenesis. The intensity and patterns of rhythmic activity are determined by nature and kinetics of certain metabolic reactions. During perinatal and sometimes postnatal periods (as in prematurely born animals), endogenic rhythmicity of developing physiological structures is strongly pronounced due to relatively stable living conditions. This rhythmic behavior is coordinated within an entire organism. Its integration in multiple systems is driven by amplitude and frequency modulation yielding rhythms of various frequency ranges. Indeed, it is the complex and conjoint functioning of physiological systems that maintains homeostasis in developing organisms. We present the results of our authentic research concerning the evolution and ontogeny of regulatory mechanisms of motor, cardiovascular, and respiratory systems. The aspects of intact and disrupted development are considered, involving the changes in dopaminergic, norepinephrinergic, and cholinergic system activation.

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“…Decelerations are superseded by acceleration reactions that are typical of a mature organism on E19-20. It is related to development of coordinating function of nervous system [22].…”

Section: Development Of Cross-system Interactions In Perinatal Ontogementioning

confidence: 99%

Ontogenetic Development of Neural and Muscular Rhythmic Activity and Its Regulation in Mammals during Perinatal Period

Кузнецов¹,

Vdovichenko²,

Dmitrieva³

et al. 2018

Evolutionary Physiology and Biochemistry - Advances and Perspectives

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“…Focusing on short phases of embryonic-maternal heart rate synchronization, a study in humans suggests that the embryonic circulatory system might be able to react to the maternal heart rate (Van Leeuwen et al 2009). This phenomenon also appears to be present in rats (Rattus norvegicus; Timofeeva et al 2015). In placental mammals, however, the embryo is provided with maternal hormones, nutrients, and oxygen via the placenta (Knipp et al 1999), providing the opportunity for the mother to directly tune embryonic heart rate, instead of the embryo reacting autonomously to the mother.…”

Section: Introductionmentioning

confidence: 99%

Does parental heart rate affect embryonic heart rate during incubation? An experiment in Common Terns Sterna hirundo

2021

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Embryonic heart rate is a strong determinant of metabolic rate and the rate of embryonic development in oviparous species. In humans, embryonic heart rate is positively correlated with the heart rate of the mother. However, human embryos do not develop autonomously from the maternal circulatory system, making it impossible to separate maternal control from an independent embryonic adjustment of its heart rate to that of its mother. In birds, embryonic development does occur autonomously from the mother, while the embryo can auditively perceive the heart rate of the incubating parent. In this study, we used Common Terns (Sterna hirundo) to experimentally test whether the embryonic heart rate is affected by parental heart rate during incubation. We artificially incubated freshly laid eggs under standardized conditions and continuously exposed them to the sound of either a slow or fast parental heart rate throughout the first 18 days of embryonic development. At day 18 of embryonic development (a few days before hatching) there was no significant difference in the embryonic heart rate between both treatments. There was also no effect of treatment on either total duration of embryonic development or hatching success. We suggest that embryonic heart rate and development rate may not be affected by the heart rate of the parent because natural parental heart rates are very sensitive to external conditions that may fluctuate drastically, while embryos may need a relatively stable heart rate for optimal development.

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Effect of Muscarinic Cholinergic Receptor Blockade on Heart Activity in Rat Fetuses

Timofeeva

Vdovichenko

2019

Bull Exp Biol Med

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Quantitative assessment of the relationship of slow-wave heart rate oscillations and motor activity in rat fetuses with maternal respiratory and cardiac activity

Cited by 3 publications

References 16 publications

Ontogenetic Development of Neural and Muscular Rhythmic Activity and Its Regulation in Mammals during Perinatal Period

Ontogenetic Development of Neural and Muscular Rhythmic Activity and Its Regulation in Mammals during Perinatal Period

Does parental heart rate affect embryonic heart rate during incubation? An experiment in Common Terns Sterna hirundo

Effect of Muscarinic Cholinergic Receptor Blockade on Heart Activity in Rat Fetuses

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