Quantitative Assessment of Neurons and Neuroglia with Computer Morphometry

Abstract

The morphology of neural and glial cells in different cerebral areas and in various experimental models was quantitatively studied by methods of computer morphometry combined with video image analysis systems. The following parameters were obtained: density of neurons and glial cells per 1 mm(2), number of satellite perineuronal glial cells, aspect ratio for neural and glial cells, the area occupied by neuroglial projections, etc. The tested computer morphometry methods can be efficient in quantitative assessment of pathological and regenerative processes in the nervous tissue.