Quantitative assessment of liver fibrosis: a novel automated image analysis method

Matalka, Ismail; Al-Jarrah, Omar; Manasrah, Toqa M.

doi:10.1111/j.1478-3231.2006.01341.x

Cited by 13 publications

(18 citation statements)

References 35 publications

(32 reference statements)

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“…Reading of necroinflammatory lesions is more reproducible with the Scheuer scale than with the Knodell HAI [13]. Recently, an automated analyzer was used to quantify the fibrosis, which seems an intelligent approach that attempts to utilize the current semiquantitative methods of liver fibrosis assessment to turn them into real quantitative ones with significant reduction in variability and subjectivity [14].…”

Section: Consensus Statementsmentioning

confidence: 99%

Liver fibrosis: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL)

et al. 2008

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Section: Consensus Statementsmentioning

confidence: 99%

Liver fibrosis: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL)

et al. 2008

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“…A laparoscopic biopsy can decrease sampling error and increase the reliability of a histopathological assessment. Using automated image analysis to assess texture features and the shape representation of the fibrosis structural expansion can turn the current semiquantitative methods of liver fibrosis assessment into real quantitative methods with significant reduction in variability and subjectivity 53 . Validating non‐invasive tests against not only histological stage scores but also digital image analysis and clinical outcomes may also be a better choice.…”

Section: Resultsmentioning

confidence: 99%

Assessment of fibrosis in chronic liver diseases

Zhou

2009

J of Digest Diseases

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The assessment of liver fibrosis provides useful information not only for diagnosis but also for therapeutic decisions. Although liver biopsy is the current gold standard for fibrosis assessment, it has some risks and limitations, including intra‐observer and inter‐observer variation, sampling error and variability. In recent years, many studies and great interest have been dedicated to the development of non‐invasive tests to substitute a liver biopsy for fibrosis assessment and follow up. Advances in serological and radiological tests such as serum marker panels, transient elastography and their combinations can assess fibrosis accurately and reduce the need for a liver biopsy. But at present, all have failed to completely replace a liver biopsy because of their respective limitations and an imperfect gold standard used in current researches. The searching for an ideal surrogate is still in progress.

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“…Laparoscopic biopsy can decrease sampling error and increases the reliability of histopathologic assessment 87 . Using automated image analysis to assess texture features and shape representation of the fibrosis structural expansion can turn the current semiquantitative methods of liver fibrosis assessment into real quantitative ones with significant reduction in variability and subjectivity 88 . Validating noninvasive tests against not only histological stage scores but also digital image analysis and clinical outcomes may also be a better choice.…”

Section: Resultsmentioning

confidence: 99%