Quantitative and qualitative coronary arteriography

Brown, B. Greg; Simpson, Paul J.; Dodge, James T.; Bolson, Edward L.; Dodge, Harold T.

doi:10.1007/978-94-011-3726-3_1

Cited by 6 publications

(2 citation statements)

References 68 publications

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“…The findings are concordant with previous studies, which allude to the smaller CAs in South Asians, although the vessel dimensions were overall of a larger calibre, with the caveat that these studies used conventional ICA. 19 30 Compared with a similar study with CCTA, the respective mean vessel diameters are greater. 11 28 30 To the authors’ knowledge, there is no published data comparing CA dimensions between these two ethnicities in the English-speaking Caribbean.…”

Section: Discussionmentioning

confidence: 77%

Comparison of cardiac CT angiography coronary artery dimensions and ethnicity in Trinidad: the CADET pilot study

et al. 2022

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BackgroundThis study aimed to determine if there were any significant differences in coronary artery (CA) dimensions at prespecified segments during cardiac CT angiography (CCTA) compared with ethnicity at an academic tertiary medical centre in Trinidad and Tobago.MethodsPatients (n=170) who underwent CCTA from July 2016 to June 2021 at the Eric Williams Medical Sciences Complex were selected based on predefined selection criteria. The size of the left main and proximal, mid and distal diameters of the left anterior descending, left circumflex and right coronary artery (RCA) were measured using quantitative coronary angiography, syngo.CT Coronary Analysis (Siemens Healthineers AG, Erlangen, Germany). Routine medical history, cardiovascular medications and anthropometric data were also recorded. Comparisons were performed using an independent sample t-test and analysis of variance for continuous variables.ResultsOne hundred and seventy participants were enrolled in this study. There were no statistically significant associations between gender and CA dimensions; however, there were significant associations between South Asian and Caribbean black ethnicities for almost all CA dimensions except for the distal RCA segment. These findings were replicated when the analysis was adjusted for body surface area with the addition of the mid-RCA segment, which was bordering near-significance (p value 0.051).ConclusionsSignificantly smaller CA dimensions were observed in South Asian patients compared with Caribbean black patients undergoing CCTA. This pilot study could be clinically significant for Trinidadian patients at risk of developing coronary artery disease.Trial registration numberNCT04774861.

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Section: Discussionmentioning

confidence: 77%

Comparison of cardiac CT angiography coronary artery dimensions and ethnicity in Trinidad: the CADET pilot study

et al. 2022

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“…Absolute and relative minimal obstructive diameters were calculated using the assumptions of Brown et al (17).…”

Section: Quantitative Coronary Angiographymentioning

confidence: 99%

Parametric assessment of myocardial perfusion during interventional cardiac catheterization by means of X-ray densitometry — short — and long-term results

et al. 1990

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X-ray densitometric evaluation of digital subtraction angiocardiograms allows an assessment of myocardial perfusion by means of the parameter 'MEAN RISE TIME' (MRT), defined as the time from the onset of local myocardial contrast medium opacification to the point of maximum opacification. Best results are obtained when the response of that parameter is compared before and after stimulation of coronary flow by papaverine. A prolongation of this parameter, especially after papaverine, was indicative of an impairment of myocardial perfusion, when compared to the results of TL-201 scintigraphy. In 50 patients with single vessel coronary artery disease the results of MRT pre and post papaverine before and after coronary angioplasty, as well as after 6 months were evaluated for 204 post-stenotic regions-of-interest. Before angioplasty papaverine induced a significant prolongation of post-stenotic MRT was measured 2.3 s +/- 0.9 s vs 3.1s +/- 0.8s; p less than 0.01), while after successful angioplasty post-stenotic MRT was measured significantly shorter after stimulation of coronary flow (2.6s +/- 1.0s vs. 1.9s +/- 0.9s; p less than 0.01). This indicated an improvement in myocardial perfusion. Nevertheless, 16/50 patients still presented pathological results of post-stenotic MRT after papaverine, although angioplasty was regarded successful. These patients presented a markedly higher rate of restenosis (14/16 patients after 6 months), a higher rate of dissections at the dilation site and a higher rate of dilated vessels, supplying myocardial areas after a Q-wave myocardial infarction. Thus, these results demonstrate the additional information about the short-and long-term outcome of an angioplasty procedure by densitometric myocardial perfusion analysis.

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Pharmacological Investigation Using Invasive Methods

Bramucci¹,

Ardissino²

1994

Developments in Cardiovascular Medicine

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Quantitative and qualitative coronary arteriography

Cited by 6 publications

References 68 publications

Comparison of cardiac CT angiography coronary artery dimensions and ethnicity in Trinidad: the CADET pilot study

Comparison of cardiac CT angiography coronary artery dimensions and ethnicity in Trinidad: the CADET pilot study

Parametric assessment of myocardial perfusion during interventional cardiac catheterization by means of X-ray densitometry — short — and long-term results

Pharmacological Investigation Using Invasive Methods

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