Quantitative and qualitative analysis of flavonoids in leaves of Adinandra nitida by high performance liquid chromatography with UV and electrospray ionization tandem mass spectrometry detection

Zhang, Jie; Yang, Jun; Duan, Jicheng; Liang, Zhen; Zhang, Lihua; Huo, Yushu; Zhang, Yukui

doi:10.1016/j.aca.2004.10.042

Cited by 43 publications

(25 citation statements)

References 23 publications

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“…nitida has great commercial interest for the food and phytopharmaceutical market, but few reports have been published about it. Zhang et al (2005) reported the identification of flavonoids in leaves of A. nitida by HPLC-MS. But in their report, the names and chemical structures of camellianin A and camellianin B were confused.…”

Section: Discussionmentioning

confidence: 99%

“…For lack of camellianin A and camellianin B, the established quality control method in the study of Zhang et al (2005) was based on the quantitative analysis of three minor flavonoids (apigenin, epicatechin and rholifolin). In our previous study (Yuan et al, 2009), the method of preparing camellianin A and camellianin B by using high-speed counter-current chromatography (HSCCC) was established.…”

Section: Discussionmentioning

confidence: 99%

“…Li (Theaceae), a wild plant in south China, is a flavonoid-rich plant source. Its leaves have been consumed as a health tea (Shiyacha) and herbal medicine for hundreds of years (Wang et al, 2003;Zhang et al, 2005). It is reported to have many curative effects such as reducing blood pressure, as well as antibacterial, antioxidant, and analgesic properties (Wang et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

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Antioxidant and angiotensin converting enzyme (ACE) inhibitory activities of ethanol extract and pure flavonoids fromAdinandra nitidaleaves

Liu

Yang

et al. 2010

Pharmaceutical Biology

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Antioxidant and angiotensin converting enzyme (ACE) inhibitory activities of ethanol extract and pure flavonoids fromAdinandra nitidaleaves

Liu

Yang

et al. 2010

Pharmaceutical Biology

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“…It is reported to have many curative effects, such as reduction of blood pressure, antibacterial, antitumor, anti-toxicity, and analgesic activities. It has been reported that the flavonoid content of its leaves could be > 20 % [1][2][3].…”

Section: Introductionmentioning

confidence: 99%

Ultrasonic-Assisted Extraction and Antioxidant Activity of Flavonoids from <i>Adinandra nitida</i> Leaves

Liu¹,

Ma²,

Liu³

et al. 2014

Trop. J. Pharm Res

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Purpose: To identify the main flavonoid in Adinandra nitida leaf, employ response surface methodology to optimize its ultrasonic-assisted extraction, and determine the antioxidant activity of the obtained extract. Methods: The main flavonoid in Adinandra nitida leaf was obtained by traditional solvent extraction and recrystallization methods, and identified by ultraviolet-visible spectroscopy (UV), Fourier transform infrared spectroscopy (FT-IR), electrospray ionization-mass spectrometry (ESI-MS), nuclear magnetic resonance spectroscopy (NMR

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“…Therefore, it commands great commercial interest in the phyto-pharmaceutical market. In some previous work, flavonoids, such as epicatechin, apigenin, quercitrin, camellianin A, and camellianin B (Table 1) [13], have been found to be the active constituents [27,28]. In this paper, with two flavonoids as markers, a CEC based quality control method for Shiyacha has been developed with monolithic rods of macroporous poly(butyl methacrylate -co-ethylene di- methacrylate) by stepwise gradient elution.…”

Section: Introductionmentioning

confidence: 99%

Analysis of flavonoids in leaves of Adinandra nitida by capillary electrochromatography on monolithic columns with stepwise gradient elution

Zhang

Jie

Wang

et al. 2005

J of Separation Science

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Extracts of Adinandra nitida leaves, known as Shiyacha in China, were analyzed by monolithic columns of capillary electrochromatography (CEC). To obtain good resolution within a short time, stepwise gradient elution of CEC was employed, and the effects of experimental parameters, such as the buffer, the gradient conditions, and the mode of injection were studied systematically. Under optimized conditions, analysis could be accomplished in 25 min on a monolithic rod of macroporous poly(butyl methacrylate-co-ethylene dimethacrylate). With two identified flavonoids, epicatechin and apigenin, as markers, a quality control method for Shiyacha and its relevant products was established. The calibration curves exhibited good linear behavior over the concentration range of two orders of magnitude. On combination with an on-line concentration technique, the detection limit of flavonoids could be decreased to 25 ng for apigenin.

show abstract

Quantitative and qualitative analysis of flavonoids in leaves of Adinandra nitida by high performance liquid chromatography with UV and electrospray ionization tandem mass spectrometry detection

Cited by 43 publications

References 23 publications

Antioxidant and angiotensin converting enzyme (ACE) inhibitory activities of ethanol extract and pure flavonoids fromAdinandra nitidaleaves

Antioxidant and angiotensin converting enzyme (ACE) inhibitory activities of ethanol extract and pure flavonoids fromAdinandra nitidaleaves

Ultrasonic-Assisted Extraction and Antioxidant Activity of Flavonoids from <i>Adinandra nitida</i> Leaves

Analysis of flavonoids in leaves of Adinandra nitida by capillary electrochromatography on monolithic columns with stepwise gradient elution

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