Quantitative analysis of the lysine acetylome reveals the role of SIRT3-mediated HSP60 deacetylation in suppressing intracellular
Mycobacterium tuberculosis
survival
Chuanzhi Zhu,
Yuheng Duan,
Jing Dong
et al.
Abstract:Protein acetylation and deacetylation are key epigenetic modifications that regulate the initiation and development of several diseases. In the context of infection with
Mycobacterium tuberculosis
(
M. tb
), these processes are essential for host–pathogen interactions and immune responses. However, the specific effects of acetylation and deacetylation on cellular functions during
M. tb
infection are not fully understood. This s… Show more
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