Quantitative analysis of surfactant deposits on human skin by liquid chromatography/electrospray ionisation tandem mass spectrometry

Abstract

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N ‐Acyl ethanolamide and eicosanoid involvement in irritant dermatitis

“…Two commonly encountered environmental stressors are sodium lauryl sulfate (SLS) and ultraviolet radiation (UVR). SLS is an anionic surfactant that deposits on human skin, which may result in irritant reactions at high doses or through long‐term exposure. At high levels (up to 20% w/v), SLS is a well‐studied positive control commonly used in vitro and in vivo to study irritant inflammation .…”

Development of novel methodologies for the identification of unknown compounds in the environment employing non-target screening and high-resolution mass spectrometry

“…Commercially available AES are complex surfactant mixtures containing anionic homologs with alkyl chain lengths ranging from 8 to 18 carbon atoms. Each homolog can exhibit varying degrees of ethoxylation ranging from 0 to 9 EO units[190]. However, the majority of AES blends manufactured, are alkyl chains in the range of C12 to C15 with 0 to 4 EO units…”

“…A high production volume example of AES is sodium lauryl ether sulfate (SLES, sometimes also named sodium laureth sulfate). SLES is the sodium salt of the C12 homolog of AES with predominantly three EO units[190]. It should not be confused with sodium dodecyl sulfate (synonymously sodium lauryl sulfate, SLS), which belongs to the group of non-ethoxylated alkyl sulfates (AS).…”