With funding from the National Science Foundation, the Center for Open Science (COS) and Indiana University will create a dynamic, distributed, and heterogeneous data source for the advancement of science of science research. This will be achieved by using, enhancing, and combining the capabilities of the Open Science Framework (OSF) and the Collaborative Archive & Data Research Environment (CADRE). With over 200,000 users (currently growing by >220 per day), many thousands of projects, registrations, and papers, millions of files stored and managed, and rich metadata tracking researcher actions, the OSF is already a very rich dataset for investigating the research lifecycle, researcher behaviors, and how those behaviors evolve in the social network. As a cross-university effort, CADRE provides an integrated data mining and collaborative environment for big bibliographic data sets. While still under development, the CADRE platform has already attracted long-term financial commitments from 10 research intensive universities with additional support from multiple infrastructure and industry partners. Connecting these efforts will catalyze transformative research of human networks in the science of science.